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Table 1 Description of the main cohort, n = 7898

From: Ever dispense of prescribed allergy medication in children growing up close to traffic: a registry-based birth cohort

  

N (%)

HR (95 % CI)a

Nasal anti-allergics

Oral antihistamine

1st purchase

1st purchase

Sex

Girl

3784 (49)

1.0

1.0

Boy

3996 (51)

1.40 (1.04–1.90)

1.03 (0.95–1.12)

Missing

118

  

Birth weight

2500–4000 (normal)

6079 (78)

1.0

1.0

500–2499 (low)

301 (4)

1.38 (0.70–2.71)

0.98 (0.78–1.22)

4001–6500 (high)

1396 (18)

0.95 (0.64–1.41)

1.02 (0.91–1.13)

Missing

122

  

Smoking during pregnancy

No

7275 (94)

1.0

1.0

Yes

499 (6)

1.07 (0.61–1.88)

1.08 (0.92–1.27)

Missing

124

  

Environmental tobacco smoke

No

6591 (85)

1.0

1.0

Yes

1177 (15)

0.89 (0.58–1.36)

0.97 (0.86–1.09)

Missing

130

  

Breastfeeding

≥8 months

3920 (56)

1.0

1.0

<8 months

2807 (40)

0.91 (0.67–1.24)

1.19 (1.09–1.30)

Never breastfed

278 (4)

0.79 (0.32–1.95)

1.08 (0.86–1.36)

Missing

893

  

Parental allergy

No

3177 (46)

1.0

1.0

Yes

3751 (54)

1.18 (0.86–1.62)

1.14 (1.05–1.25)

Missing

970

  

Furred pets at home

No

5790 (75)

1.0

1.0

Yes

1922 (25)

1.12 (0.80–1.56)

1.13 (1.03–1.25)

Missing

186

  

Mold at home

No

7326 (95)

1.0

1.0

Yes

386 (5)

1.26 (0.69–2.32)

0.99 (0.81–1.20)

Missing

186

  

Problems to pay bills

Never or seldom

7361 (96)

1.0

1.0

Yes, >6 months/year

348 (5)

0.84 (0.40–1.80)

0.92 (0.75–1.14)

Missing

189

  

Swedish parents

Yes, both Swedish

297 (4)

1

1.0

One foreign

1792 (23)

1.03 (0.68–1.55)

0.93 (0.83–1.04)

Both foreign

5612 (73)

1.16 (0.81–1.66)

0.80 (0.72–0.89)

Missing

197

  

Highest education any parent

>12 years

297 (4)

1.0

1.0

10–12 years

1792 (23)

1.14 (0.48–2.68)

1.13 (0.89–1.44)

≤9 years

5612 (73)

1.22 (0.54–2.76)

1.16 (0.92–1.47)

Missing

   

Type of housing

Owned house

2384 (36)

1.0

1.0

Tenant-owned apartment

2242 (29)

0.69 (0.47–1.01)

0.93 (0.84–1.03)

Rented apartment

2616 (34)

0.84 (0.60–1.18)

0.86 (0.78–0.95)

Other

101 (1)

---

1.14 (0.80–1.61)

Missing

156

  

Municipality

Vellinge

449 (6)

1.0

1.0

Svedala

664 (8)

0.70 (0.35–1.42)

1.25 (1.01–1.53)

Trelleborg

611 (8)

0.65 (0.39–1.08)

0.81 (0.69–0.96)

Malmö

6134 (78)

0.65 (0.32–1.32)

1.01 (0.82–1.25)

Missing

40

  

Birth year

2005

1066 (14)

1.0

1.0

2006

2395 (30)

1.94 (1.18–3.19)

1.22 (1.07–1.39)

2007

1664 (21)

1.66 (0.90–3.04)

1.10 (0.95–1.28)

2008

2179 (28)

2.56 (1.34–4.90)

1.17 (1.01–1.35)

2009

594 (8)

2.44 (0.68–8.77)

1.48 (1.19–1.84)

Birth season

Winter (Dec–Feb)

1957 (25)

1.0

1

Spring (March–May)

1946 (25)

1.12 (0.76–1.67)

1.02 (0.91–1.15)

Summer (June–Aug)

1835 (23)

0.47 (0.30–0.73)

0.85 (0.75–0.95)

Autumn (Sep–Nov)

2160 (27)

0.59 (0.40–0.88)

0.87 (0.78–0.98)

  1. HR (95 % CI) for dispense of medication in relation to population characteristics, for people who may have moved during study time
  2. aUnadjusted --- Too few individuals, numerically unstable results