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Table 1 Description of the main cohort, n = 7898

From: Ever dispense of prescribed allergy medication in children growing up close to traffic: a registry-based birth cohort

   N (%) HR (95 % CI)a
Nasal anti-allergics Oral antihistamine
1st purchase 1st purchase
Sex Girl 3784 (49) 1.0 1.0
Boy 3996 (51) 1.40 (1.04–1.90) 1.03 (0.95–1.12)
Missing 118   
Birth weight 2500–4000 (normal) 6079 (78) 1.0 1.0
500–2499 (low) 301 (4) 1.38 (0.70–2.71) 0.98 (0.78–1.22)
4001–6500 (high) 1396 (18) 0.95 (0.64–1.41) 1.02 (0.91–1.13)
Missing 122   
Smoking during pregnancy No 7275 (94) 1.0 1.0
Yes 499 (6) 1.07 (0.61–1.88) 1.08 (0.92–1.27)
Missing 124   
Environmental tobacco smoke No 6591 (85) 1.0 1.0
Yes 1177 (15) 0.89 (0.58–1.36) 0.97 (0.86–1.09)
Missing 130   
Breastfeeding ≥8 months 3920 (56) 1.0 1.0
<8 months 2807 (40) 0.91 (0.67–1.24) 1.19 (1.09–1.30)
Never breastfed 278 (4) 0.79 (0.32–1.95) 1.08 (0.86–1.36)
Missing 893   
Parental allergy No 3177 (46) 1.0 1.0
Yes 3751 (54) 1.18 (0.86–1.62) 1.14 (1.05–1.25)
Missing 970   
Furred pets at home No 5790 (75) 1.0 1.0
Yes 1922 (25) 1.12 (0.80–1.56) 1.13 (1.03–1.25)
Missing 186   
Mold at home No 7326 (95) 1.0 1.0
Yes 386 (5) 1.26 (0.69–2.32) 0.99 (0.81–1.20)
Missing 186   
Problems to pay bills Never or seldom 7361 (96) 1.0 1.0
Yes, >6 months/year 348 (5) 0.84 (0.40–1.80) 0.92 (0.75–1.14)
Missing 189   
Swedish parents Yes, both Swedish 297 (4) 1 1.0
One foreign 1792 (23) 1.03 (0.68–1.55) 0.93 (0.83–1.04)
Both foreign 5612 (73) 1.16 (0.81–1.66) 0.80 (0.72–0.89)
Missing 197   
Highest education any parent >12 years 297 (4) 1.0 1.0
10–12 years 1792 (23) 1.14 (0.48–2.68) 1.13 (0.89–1.44)
≤9 years 5612 (73) 1.22 (0.54–2.76) 1.16 (0.92–1.47)
Missing    
Type of housing Owned house 2384 (36) 1.0 1.0
Tenant-owned apartment 2242 (29) 0.69 (0.47–1.01) 0.93 (0.84–1.03)
Rented apartment 2616 (34) 0.84 (0.60–1.18) 0.86 (0.78–0.95)
Other 101 (1) --- 1.14 (0.80–1.61)
Missing 156   
Municipality Vellinge 449 (6) 1.0 1.0
Svedala 664 (8) 0.70 (0.35–1.42) 1.25 (1.01–1.53)
Trelleborg 611 (8) 0.65 (0.39–1.08) 0.81 (0.69–0.96)
Malmö 6134 (78) 0.65 (0.32–1.32) 1.01 (0.82–1.25)
Missing 40   
Birth year 2005 1066 (14) 1.0 1.0
2006 2395 (30) 1.94 (1.18–3.19) 1.22 (1.07–1.39)
2007 1664 (21) 1.66 (0.90–3.04) 1.10 (0.95–1.28)
2008 2179 (28) 2.56 (1.34–4.90) 1.17 (1.01–1.35)
2009 594 (8) 2.44 (0.68–8.77) 1.48 (1.19–1.84)
Birth season Winter (Dec–Feb) 1957 (25) 1.0 1
Spring (March–May) 1946 (25) 1.12 (0.76–1.67) 1.02 (0.91–1.15)
Summer (June–Aug) 1835 (23) 0.47 (0.30–0.73) 0.85 (0.75–0.95)
Autumn (Sep–Nov) 2160 (27) 0.59 (0.40–0.88) 0.87 (0.78–0.98)
  1. HR (95 % CI) for dispense of medication in relation to population characteristics, for people who may have moved during study time
  2. aUnadjusted --- Too few individuals, numerically unstable results
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