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Table 4 Summary of change in smoking urge parameters and statistical comparisons to the tobacco cigarette

From: Nicotine delivery, tolerability and reduction of smoking urge in smokers following short-term use of one brand of electronic cigarettes

 

E-Cigarettes

 

Smoking Urge Parameters

2.4 % nic + Gly

2.4 % nic + Gly/PG

2.4 % nic + Gly + menthol

1.6 % nic + Gly

1.6 % nic + Gly/PG

Tobacco Cigarette

N = 23

N = 23

N = 23

N = 23

N = 23

N = 24

Emax0–30 (mm)

−41.9 ± 26.56

−44.7 ± 26.98

−37.0 ± 30.25

−40.2 ± 32.47

−40.7 ± 24.25

−41.5 ± 27.43

p-value

0.9285

0.6427

0.3023

0.6972

0.7450

 

Emaxreduction0–30 (mm)

−42.2 ± 26.01

−44.7 ± 26.98

−39.1 ± 25.86

−41.4 ± 30.40

−40.7 ± 24.25

−41.7 ± 27.08

p-value

0.9489

0.6505

0.5056

0.8480

0.7079

 

AUEC0–30 (hr*mm)

−14.1 ± 10.56

−15.5 ± 10.39

−12.2 ± 10.75

−13.9 ± 12.09

−13.3 ± 8.29

−15.4 ± 12.67

p-value

0.4054

0.8912

0.0882

0.3590

0.2225

 

TEmax0–30 (hr)

0.41 (0.07, 0.50)

0.41 (0.07, 0.50)

0.41 (0.08, 0.50)

0.42 (0.08, 0.50)

0.49 (0.24, 0.50)

0.25 (0.07, 0.51)

p-value

0.1764

0.0948

0.0014

0.0012

0.0009

 

AUEC30–90 (hr*mm)

−44.3 ± 35.39

−50.9 ± 33.64

−42.7 ± 38.24

−46.2 ± 40.23

−47.7 ± 34.16

−46.9 ± 30.14

p-value

0.6679

0.5275

0.5046

0.8919

0.9395

 

E90 (mm)

−37.0 ± 30.69

−42.5 ± 29.85

−34.3 ± 34.03

−37.4 ± 35.08

−38.5 ± 30.12

−52.2 ± 26.33

p-value

0.0060

0.0921

0.0010

0.0066

0.0122

 
  1. TEmax0–30 is presented as median (minimum, maximum), all other values are presented as arithmetic mean ± SD. Statistical significance is based on the differences in least squares means between groups. P-values represent the comparison to the tobacco cigarette
  2. nic nicotine, Gly glycerine, PG propylene glycol
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BMC Public Health

ISSN: 1471-2458

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