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Table 6 TES laboratory-based BOEa among smokers and non-users, and among those with and without banked biospecimens

From: Total Exposure Study Analysis consortium: a cross-sectional study of tobacco exposures

 

All

With

Without

t

P

Among smokers

     

NE per cigb

0.89 (0.7)

0.91 (0.7)

0.86 (0.7)

2.33

.020

NE mg/24 hrc

12.78 (7.9)

13.3 (7.9)

11.76 (7.8)

5.48

<.0001

Serum cotinine ng/mld

188.9 (103.4)

190.0 (103.1)

186.7 (147.7)

0.9

.37

Total NNAL ng/cige

29.4 (23.7)

30.3 (23.9)

27.8 (23.1)

3.03

.0025

Total NNAL ng/24 hrf

425.2 (303.9)

445.5 (308.2)

385.7 (291.5)

5.67

<.0001

COHb % saturationg

5.26 (2.3)

5.35 (2.3)

5.09 (2.3)

3.25

.0012

1-OHP ng/24 hrh

259.8 (345)

268.3 (343)

243.3 (349)

2.32

.02

3-HPMA ug/24 hri

1941.9 (1326)

2017.6 (1302)

1796.6 (1361)

4.73

<.0001

4-ABP pg/g Hbj

43.5 (53.6)

44.2 (56.8)

42.3 (47.1)

0.96

.34

MHBMA ug/24 hrk

3.52 (3.3)

3.60 (3.3)

3.38 (3.4)

1.87

.062

DHBMA ug/24 hrl

530.1 (276.3)

541.1 (255.7)

508.9 (311.2)

3.11

.0019

Among non-smokers

     

COHb % saturationm

1.46 (0.5)

1.46 (0.6)

1.45 (0.5)

0.08

.94

3-HPMA ug/24 hrn

461.7 (532)

484.3 (571)

416.3 (441.0)

2.14

.033

4-ABP pg/g Hbo

14.5 (70.8)

13.2 (71.5)

17.0 (69.6)

−0.68

.5

MHBMA ug/24 hrp

0.49 (1.0)

0.48 (0.8)

0.50 (1.3)

−0.16

.88

DHBMA ug/24 hrq

385.6 (172.5)

398.8 (182.3)

359.1 (147.7)

3.82

<.0001

  1. aDefinitions (and parent compounds) of BOE from Additional file 2: Table S1: NE Nicotine Equivalents (Nicotine); Total NNAL Total 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, and its glucuronide (4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone); COHb carboxyhemoglobin (carbon monoxide); 1-OHP Total 1-hydroxypyrene (polycyclic aromatic hydrocarbons); 3-HPMA 3-hydroxy-propylmercapturic acid (acreolein); 4-ABP 4-aminobiphenyl hemoglobin (Hb) adducts (4-aminobiphenyl); MHBMA monohydroxyl-butenylmercapturic acid (1,3 butadiene); DHBMA = dihydroxy-butyl-mercapturic acid (1,3 butadiene)
  2. bN = 3529, d = 0.10. cN = 3535, d = 0.18. dN = 3469. eN = 3529, d = 0.11. fN = 3535, d = 0.20. gN = 3558, d = 0.11. hN = 3554, d = 0.07. iN = 3556, d = 0.17. jN = 2801. kN = 3415. lN = 3558, d = 0.11. mN = 1069. nN = 1058, d = 0.13. oN = 723. pN = 629. qN = 1074, d = 0.24