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Table 1 Summary of included studies on antimicrobial self-medication in LMICs

From: Household antimicrobial self-medication: a systematic review and meta-analysis of the burden, risk factors and outcomes in developing countries

Study

Country

Recall period/Weeks

Prevalence of SM ( %)

Incorrect drug use

Outcomes

Disease symptoms treated

Abdo-Rabbo, 2003

Yemen

NR

4 %

NR

NR

Fever (4 %)

Agbor (2011)

Cameroon

NR

21.2 %

 

Symptoms resolved in a week (39.7 %)

Tooth ache (54.7 %), gingival bleeding (13 %)

Al-Azzam, 2007

Jordan

4

9.5 %

NR

NR

RTIs (39.1 %), GIT (4.9 %), UTIs (2.9 %), Ear (1.3 %)

Askarian, 2012

Iran

52

43.7 %

NR

NR

RTIs (73.1 %, GIT (41 %)

Auta, 2012

Nigeria

3

17.9 %

NR

NR

NR

Awad, 2005

Sudan

4

73.7 %

Inadequate dose (39 %), Short duration (39 %)

NR

RTIs (20.1 %), fever/malaria (5.5 %)

Bano, 2012

Pakistan

NR

55 %

Wrong dose, short duration

NR

RTIs (41.3 %), fever/malaria (80 %), GIT (61.3 %), Skin (72.6 %)

Barah, 2010

Syria

4

48.4 %

Stop taking drugs when symptoms improve (50 %)

Allergies (13 %), failed to cure (10 %)

NR

Chowdhury, 2009

Bangladesh

24

18.3 %

Stopped taking drugs when felt better (3.6 %)

Symptoms resolved (2.2 %)

Fever/malaria (55 %), GIT (9 %), Skin (11 %)

de Oliveira, 2004

Brazil

NR

10.1 %

Incorrect use (0.5 %)

Symptoms did not resolve (3.5 %)

NR

Deressa, 2003

Ethiopia

24

17.8 %

Dose not completed (4.3 %)

NR

Fever/malaria (97 %)

Enato, 2011

Nigeria

2

44.9 %

NR

Symptoms resolved (96 %)

Fever/malaria (57.6 %)

Hussain, 2011

Pakistan

12

17.8 %

NR

NR

RTIs (14.5 %), fever/malaria (57.6 %), GIT (8.4 %), Skin (8.6 %)

Jassim, 2010

Iraq

NR

63.5 %

Dose not completed (54 %), sharing drugs (12 %)

NR

RTIs (11.3 %), fever/malaria (8.1 %), GIT (11.3 %), Skin (4.9 %), UTIs (4.1 %), Ear (3.6 %)

Jombo, 2011

W. Africa

NR

38.4 %

NR

NR

NR

Lima, 2010

Brazil

NR

69.2 %

Sharing drugs

NR

RTIs, GIT

Mossa, 2012

Ethiopia

12

14.6 %

NR

NR

RTIs (14.1 %), fever/malaria (35.9 %), GIT (10.2 %)

Nounon, 2009

Argentina

NR

53.1 %

Stopped taking drugs when felt better (14 %)

Symptoms resolved (4 %)

RTIs (48 %), fever/malaria (18 %), Skin (1 %), UTIs (7 %)

Ngasha, 2011

Cameroon

NR

55.7 %

NR

Symptoms did not resolve

Fever/malaria

Okumura, 2002

Vietnam

NR

12.7 %

NR

NR

RTIs (3.1 %), GIT (1.6 %)

Onanuga, 2011

Nigeria

NR

45 %

Not completed dose (16.7 %), stopped taking drugs when symptoms resolved (28.3 %)

Experienced adverse effects (65.8 %)

NR

Onohwosafe, 2013

Nigeria

NR

54.8 %

NR

NR

Fever/malaria (49.6 %)

Osemene, 2012

Nigeria

NR

91.4 %

NR

NR

RTIs (15.3 %), fever/malaria (5.5 %), GIT (10.2 %), UTIs (43.5 %), Ear (2 %)

Oyetunde, 2010

Nigeria

NR

25.9 %

Short duration (90 %)

NR

NR

Omole, 2010

Nigeria

12

35.7 %

NR

Not cured (33.7 %), cured (12.9 %)

Fever/malaria, GIT

Sanjana, 2006

Indonesia

52

42 %

NR

Adverse effects (23 %), relapse of malaria

Fever/malaria (93 %), GIT (17 %)

Sapkota, 2010

Nigeria

12

25.2 %

NR

NR

None specific symptoms

Sarahroodi, 2009

Iran

12

54.5 %

Not completing dose (74.2 %)

NR

RTIs (66.7 %), GIT (23 %)

Sawalha, 2008

Palestine

24

19.4 %

Not completing dose (59.9 %)

NR

RTIs (30.3 %), Ear (3.3 %)

Shankar, 2002

Nepal

24

59.2 %

NR

NR

Fever/malaria

Shehadeh, 2012

Jordan

52

30 %

Not completing dose (38.5 %)

ADRs (69.6 %), Allergy, harm the teeth

RTIs (31 %), UTIs (4.7 %), Ear (3.8 %)

Sihavong, 2006

LPR

52

91 %

Short duration of taking drugs (79 %)

NR

UTIs (78 %)

Widayati, 2011

Indonesia

4

8.1 %

Short duration of taking drugs (36.6 %)

NR

RTIs (31.8 %), fever/malaria (12.2 %)

Yousif, 2002

Sudan

NR

46.9 %

Sharing drugs (59.3 %), Not completing dose (28.8 %)

NR

NR

  1. LMICs: Low and Middle Income countries, NR: Not Reported, RTIs: Respiratory Tract Infections, GIT: Gastrointestinal tract, UTIs: Urinary Tract Infections, LPR: Lao People’s Republic