Design and baseline characteristics of the PerfectFit study: a multicenter cluster-randomized trial of a lifestyle intervention in employees with increased cardiovascular risk

Table 2 Baseline characteristics of the study population (demographics, health and work-related factors) in two intervention arms

	Limited Intervention	Extensive Intervention	P value
	n = 218	n = 275
Age, mean (sd)	52.1 (6.0)	50.7 (5.4)	<0.006^*
Organization			0.007
Police	124 (57.1)	138 (50.4)
Military	60 (27.6)	110 (40.1)
Hospital	33 (15.2)	26 (9.5)
Gender:
Male	154 (77.0 %)	226 (84.6 %)	0.036^*
Educational level			0.011^*
Low	33 (17.5 %)	33 (12.6 %)
Medium	116 (61.4 %)	140 (53.6 %)
High	40 (21.2 %)	88 (33.7 %)
Hypertension^a	73 (35.1 %)	100 (38.2 %)	0.493
Body Mass Index category
<25 kg/m2	64 (29.9 %)	64 (24.4 %)	0.294
25-30 kg/m2	117 (54.7 %)	147 (56.1 %)
>30 kg/m2	33 (15.4 %)	51 (19.5 %)
Waist circumference, cm :
High (female >88 cm; male >102 cm)	79 (39.7 %)	122 (46.0 %)	0.173
Obesity^b	81 (40.7 %)	128 (48.9 %)	0.082
Family history of CVD^c	78 (38.0 %)	104 (39.4 %)	0.767
Diabetes mellitus (DM) type II^d	8 (3.9 %)	6 (2.3 %)	0.314
Dyslipidemia^e	197 (91.6 %)	251 (93.3 %)	0.484
Health risk behavior:
Lack of physical activity	73 (35.6 %)	96 (36.9 %)	0.770
Smoking	23 (11.1 %)	49 (18.6 %)	0.026^*
Framingham 10-year CVD risk score category^f
Low (<10 %)	123 (66.5 %)	182 (72.2 %)	0.430
Intermediate (≥10 %, <20 %)	52 (28.1 %)	58 (23 %)
High (≥20 %)	10 (5.4 %)	12 (4.8 %)
Number of inclusion criteria:
1	43 (20.3 %)	41 (15.0 %)	0.323
2	64 (30.2 %)	87 (31.9 %)
3	63 (29.7 %)	77 (28.2 %)
≥4	42 (19.8 %)	68 (24.9 %)

^*statistically different, continuous measurements based on ANOVA test, categorical measurements based on Chi-Square test
^aHypertension is defined as diastolic blood pressure higher than 90 mmHG or systolic blood pressure higher than 140mmHG or taking antihypertensive drugs
^bObesity is defined as BMI >30 kg/m² or waist circumference >88 cm for females or >102 cm for males
^cFamily history of CVD is defined as a first degree family member who suffered a CVD at any age
^dDiabetes is defined as having a sober blood glucose higher than 6.1 or self-reported diagnosis of diagnosis
^eDyslipidemia is defined as having increased levels of at least one type of lipids in the blood (total cholesterol ≥ 5 mmol/l, or LDL cholesterol ≥ 2.5 mmol/l; or triglycerides: ≥ 1.7,mmol/l, or HDL cholesterol: ≤ 1.0 mmol/l)
^fEuroSCORE and QRISK2 will be calculated after completion of the intervention, at 12 months

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