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Table 2 Adverse events reported in the included studies

From: Combination therapy of varenicline with nicotine replacement therapy is better than varenicline alone: a systematic review and meta-analysis of randomized controlled trials

 

Varenicline + nicotine patch n (%)a

Varenicline + placebo patch n (%)a

OR (95 % CI)a

Nausea

123 (28.4)

113 (25.7)

1.15 (0.85, 1.56)

Insomnia

83 (18.7)

69 (15.4)

1.27 (0.89, 1.80)

Abnormal dreams

51 (13.6)

44 (10.7)

1.20 (0.78, 1.84)

Headache

30 (7.1)

30 (7.8)

1.01 (0.60, 1.72)

  1. aPooled event rates and odds ratios calculated by fixed effect model