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Table 3 Cytological diagnosis for screened women stratified by age

From: Impact of opportunistic testing in a systematic cervical cancer screening program: a nationwide registry study

Ā 

Screened after invitation1

Routine opportunistic testing2

Ā 

Sporadic opportunistic testing3

Ā 
Ā 

n/N4

%

n/N5

%

PPD % (95 % CI)6

PPR (95 % CI)7

n/N8

%

PPD % (95 % CI)9

PPR (95 % CI)10

Cytological diagnosis

Ā Ā Ā Ā Ā Ā Ā Ā Ā Ā 

Normal cells

Ā Ā Ā Ā Ā Ā Ā Ā Ā Ā 

23-28

92,693/104,448

(88.7)

32,034/36,357

(88.1)

-0.6 (-1.0;-0.2)

0.99 (0.98;1.00)

9,141/10,417

(87.8)

-0.6 (-1.6;-0.2)

0.99 (0.98;1.00)

29-34

87,023/93,912

(92.7)

33,615/36,896

(91.1)

-1.6 (-2.0;-1.2)

0.98 (0.98;1.00)

11,887/13,004

(91.4)

-1.3 (-1.8;-0.8)

0.99 (0.98;1.00)

35-42

149,489/158,989

(94.0)

40,764/44,098

(92.4)

-1.6 (-1.9;-1.3)

0.98 (0.98;0.99)

16,960/18,280

(92.8)

-1.2 (-1.6;-0.8)

0.99 (0.98;0.99)

43-49

149,650/157,444

(95.0)

30,384/32,427

(93.7)

-1.3 (-1.6;-1.0)

0.99 (0.98;0.99)

15,878/16,889

(94.0)

-1.0 (-1.4;-0.6)

0.98 (0.99;1.00)

HSIL

Ā Ā Ā Ā Ā Ā Ā Ā Ā Ā 

23-28

1,762/104,448

(1.7)

778/36,357

(2.1)

0.4 (-0.8;1.6)

1.27 (1.17;1.38)

156/10,417

(1.5)

-0.2 (-2.2;1.8)

0.89 (0.75;1.04)

29-34

1,217/93,912

(1.3)

631/36,896

(1.7)

0.4 (-0.8;1.6)

1.26 (1.15;1.39)

105/13,004

(0.8)

-0.5 (-0.2;1.3)

0.59 (0.49;0.73)

35-42

1,242/158,989

(0.8)

552/44,098

(1.3)

0.5 (-0.6;1.6)

1.60 (1.45;1.77)

89/18,280

(0.5)

-0.3 (-1.8;1.2)

0.62 (0.50;0.77)

43-49

570/157,444

(0.4)

267/32,427

(0.8)

0.4 (-0.8;1.6)

2.27 (1.97;2.63)

58/16,889

(0.3)

-0.1 (-1.6;1.4)

0.95 (0.72;1.24)

Carcinoma in situ + AIS

Ā Ā Ā Ā Ā Ā Ā Ā Ā Ā 

23-28

22/104,448

(0.02)

8/36,357

(0.02)

0.0 (-1.4;1.4)

1.05 (0.47;2.35)

2/10,417

(0.02)

0.0 (-2.0;2.0)

0.91 (0.21;3.88)

29-34

30/93,912

(0.03)

19/36,896

(0.05)

0.02 (-1.2;1.2)

1.61 (0.91;2.86)

5/13,004

(0.04)

0.01 (-1.8;1.9)

1.20 (0.47;3.10)

35-42

37/158,989

(0.02)

15/44,098

(0.03)

0.01 (-0.9;0.9)

1.46 (0.80;2.66)

6/18,280

(0.03)

0.01 (-1.4;1.4)

1.41 (0.60;3.34)

43-49

17/157,444

(0.01)

3/32,427

(0.01)

0.0 (-1.2;1.2)

0.86 (0.25;2.92)

1/16,889

(0.01)

NA

0.55 (0.07;4.12)

Carcinoma11

Ā Ā Ā Ā Ā Ā Ā Ā Ā Ā 

23-28

4/104,448

(0.00)

3/36,357

(0.01)

0.01 (-1.1;1.1)

2.16 (0.48;9.63)

1/10,417

(0.01)

NA

2.51 (0.28;22.4)

29-34

9/93,912

(0.01)

6/36,896

(0.02)

0.01 (-1.2;1.3)

1.70 (0.60;4.77)

0/13,004

(0.00)

NA

NA

35-42

17/158,989

(0.01)

20/44,098

(0.05)

0.04 (-1.0;1.1)

4.18 (2.19;7.99)

0/18,280

(0.00)

NA

NA

43-49

12/157,444

(0.01)

13/32,427

(0.04)

0.03 (-1.2;1.3)

5.26 (2.40;11.5)

1/16,889

(0.01)

NA

0.78 (0.10;5.97)

  1. HSIL: high-grade squamous intraepithelial lesion, AIS: adenocarcinoma in situ, NA: Not available due to limited data
  2. 1) Cervical cytology obtained within 270Ā days after latest invitation.
  3. 2) Cervical cytology obtained between 271Ā days to 3Ā years after latest invitation or 2.5 to 3Ā years after latest cervical cytology.
  4. 3) Cervical cytology obtained less than 2.5Ā years after latest cervical cytology.
  5. 4) n: number of women with the cytological diagnosis within the age group, N:all women screened after invitation in the age group.
  6. 5) n: number of women with the cytological diagnosis within the age group, N:all women being routing opportunistic tested in the age group.
  7. 6) Prevalence proportion difference (%) for ā€œroutine opportunistic testingā€ compared to ā€œscreened after invitationā€.
  8. 7) Prevalence proportion ratio for ā€œroutine opportunistic testingā€ compared to ā€œscreened after invitationā€.
  9. 8) n: number of women with the cytological diagnosis within the age group, N:all women being sporadic opportunistic tested in the age group.
  10. 9) Prevalence proportion difference (%) for ā€œsporadic opportunistic testingā€ compared to ā€œscreened after invitationā€.
  11. 10) Prevalence proportion ratio for ā€œsporadic opportunistic testingā€ compared to ā€œscreened after invitationā€
  12. 11) Carcinoma including squamous and carcinoma adenocarcinoma.
  13. Statically significant results are shown in bold