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Table 2 Cytological diagnosis for women screened after invitation and women undergoing routine or sporadic opportunistic testing

From: Impact of opportunistic testing in a systematic cervical cancer screening program: a nationwide registry study

  Screened after invitation1 Routine opportunistic testing2   Sporadic opportunistic testing3  
n = 514,833 (71.2 %) n = 149,778 (20.7 %)   n = 58,590 (8.1 %)
  n % n % PPD % (95 % CI)4 PPR (95 % CI)5 n % PPD % (95 % CI)6 PPR (95 % CI)7
Cytological diagnosis
Normal cells 478,855 (93.0) 136,797 (91.3) −1.7 (−1.87; −1.52) 0.98 (0.98;0.98) 53,866 (91.9) −1.1 (−1.34; −0.86) 0.99 (0.99;0.99)
ASCUS 10,868 (2.1) 3,674 (2.5) 0.4 (−0.17; 0.95) 1.16 (1.12;1.21) 1,361 (2.3) 0.2 (−0.64;1.04) 1.10 (1.04;1.16)
ASC-H 2,175 (0.4) 846 (0.6) 0.2 (−0.38; 0.78) 1.34 (1.24;1.45) 250 (0.4) 0.0 (−0.83; 0.83) 1.01 (0.89;1.15)
AGC 634 (0.1) 236 (0.2) 0.1 (−0.52; 0.72) 1.28 (1.10;1.49) 99 (0.2) 0.1 (−0.81; 1.01) 1.37 (1.11;1.70)
LSIL 7,857 (1.5) 2,760 (1.8) 0.3 (−0.26; 0.86) 1.21 (1.16;1.26) 945 (1.6) 0.1 (−0.74; 0.94) 1.06 (0.99;1.13)
HSIL 4,791 (0.9) 2,228 (1.5) 0.6 (0.03; 1.17) 1.60 (1.52;1.68) 408 (0.7) −0.2 (−1.05; 0.65) 0.75 (0.68;0.83)
Carcinoma in situ + AIS 106 (0.02) 45 (0.03) 0.01 (−0.56; 0.58) 1.46 (1.00;2.07) 14 (0.02) 0.0 (−0.79; 0.79) 1.16 (0.66;2.03)
Carcinoma8 42 (0.01) 42 (0.03) 0.02 (−0.58; 0.62) 3.44 (2.24;5.27) 2 (0.0) −0.01 (−0.31; 0.29) 0.42 (0.10;1.72)
Inadequate cervical cytology9 9,109 (1.8) 2,988 (2.0) 0.2 (−0.37; 0.77) 1.13 (1.08;1.17) 1,538 (2.6) 0.8 (−0.04; 1.64) 1.48 (1.40;1.56)
Others10 29 (0.01) 8 (0.01) 0.0 (−0.78; 0.78) 0.95 (0.43;2.07) 1 (0.0) NA NA
  1. Numbers and proportion vary because of missing data.
  2. ASCUS: atypical squamous cells of undetermined significance; ASC-H: atypical squamous cells, cannot exclude high-grade squamous intraepithelial lesion (HSIL); AGC: atypical glandular cells; LSIL: low-grade squamous intraepithelial lesion; HSIL: high-grade squamous intraepithelial lesion; AIS: adenocarcinoma in situ. NA: Not available due to limited data;
  3. Statically significant results are shown in bold.
  4. 1) Cervical cytology obtained within 270 days after latest invitation.
  5. 2) Cervical cytology obtained between 271 days to 3 years after latest invitation or 2.5 to 3 years after latest cervical cytology.
  6. 3) Cervical cytology obtained less than 2.5 years after latest cervical cytology.
  7. 4) Prevalence proportion difference (%) for “routine opportunistic testing” compared to “screened after invitation”.
  8. 5) Prevalence proportion ratio for “routine opportunistic testing” compared to “screened after invitation”.
  9. 6) Prevalence proportion difference (%) for “sporadic opportunistic testing” compared to “screened after invitation”.
  10. 7) Prevalence proportion ratio for “sporadic opportunistic testing” compared to “screened after invitation”.
  11. 8) Carcinoma including squamous and carcinoma adenocarcinoma.
  12. 9) Not suitable for diagnosis
  13. 10) Necrosis