Table 3 Univariate and multivariate analysis of risk factors for RIF resistance in M. tuberculosis complex isolates from retreatment cases around Jimma, Southwest Ethiopia from March 2012 to April 2013 (n = 70)
Variables | Rifampicin resistance | COR (95 % CI) | p-value | AOR (95 % CI) | p-value | |
|---|---|---|---|---|---|---|
Yes | No | |||||
HIV sero-status | ||||||
Positive | 11 (47.8 %) | 12 (52.2 %) | 2.67 (0.937, 7.63) | 0.066 | 2.89 (0.97, 8.64) | 0.057 |
Negative | 11 (23.4 %) | 36 (76.6 %) | 1 | 1 | ||
Retreatment sub-categories | ||||||
Treatment failure and defaulters | 16 (43.2 %) | 21 (56.8 %) | 2.8 (0.98, 8.15) | 0.054 | 3.04 (1.02, 9.10) | 0.047 |
Relapse | 7 (21.2 %) | 26 (78.8 %) | 1 | 1 | ||
Alcohol abuse | ||||||
Yes | 5 (55.6 %) | 4 (44.4 %) | 2.99 (0.72, 12.42) | 0.143 | 2.89 (0.61, 13.58) | 0.180 |
No | 18 (29.5 %) | 43 (70.5 %) | 1 | |||
History of being in prison | ||||||
Yes | 6 (50 %) | 6 (50 %) | 2.41 (0.68, 5.55) | 0.189** | 1.8 (0.43, 7.57) | 0.421 |
No | 23 (39.7 %) | 35 (60.3 %) | 1 | 1 | ||