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Table 2 Univariate and multivariate cox- regression analysis to predict postcessational weight gain of more than 5 % of baseline body weight within 24 months (n = 654)

From: Predictors of marked weight gain in a population of health care and industrial workers following smoking cessation

n = 654   Univariate cox -regression analysis    Multivariate cox-regression analysis  
Variables HR 95 % CI p HR 95 % CI p
Demographics       
Age (30 vs. 50 years) 1.00 0.99-1.02 0.59 1.00 0.97-1.03 0.94
BMI (20 vs. 30) 0.45 0.35-0.85 0.02 0.60 0.40-0.80 0.03
Gender       
Male ---- ---- ---- --- --- ---
Female 1.42 1.07-1.87 0.01 1.40 0.93-2.10 0.11
Civil status       
Single) ---- ---- ---- --- --- ---
Married 0.97 0.64-1.46 0.88 --- --- ---
Divorced 0.78 0.44-1.39 0.46 --- --- ---
Widowed 1.40 0.46-4.17 0.55 --- --- ---
Education       
University ---- ---- ---- --- --- ---
Apprenticeship 1.97 1.20-3.24 <0.01 2.60 1.60-5.50 <0.01
Basic education 3.02 1.60-5.36 <0.01 2.90 1.39-4.83 <0.01
Comorbidities       
Arterial Hypertension 0.99 0.52-1.91 1.00 1.05 0.51-2.18 0.89
Coronary heart disease 0.34 0.12-0.95 0.02 0.21 0.07-0.62 <0.01
Diabetes mellitus 2.22 1.11-6.01 0.04 3.05 2.20-8.06 0.02
Malignancy 1.01 0.44-2.32 0.98 0.61 0.25-1.50 0.28
Epilepsy 1.08 0.78-1.86 0.78 1.42 0.5-1.32 0.45
Antidepressant medication 0.93 0.62-1.40 0.73 0.89 0.54-1.46 0.64
Psychiatric disorder 1.19 0.78-1.80 0.41 1.07 0.62-1.85 0.79
Satisfaction with Life (Qol), (points) 0.98 0.95-1.01 0.26 0.98 0.95-1.02 0.42
Respiratory Symptoms       
Cough 1.02 0.99-1.04 0.18 1.00 0.90-1.08 0.42
Sputum 1.50 1.08-2.07 0.01 1.32 0.89-1.95 0.17
Wheezing 1.23 1.10-2.34 0.26 1.31 1.09-1.17 0.35
Breathlessness at rest 1.59 0.94-2.69 0.09 1.29 0.65-2.55 0.47
Breathlessness at exertion 1.04 0.78-1.37 0.80 0.93 0.66-1.30 0.66
Smoking related history       
Number of cigarettes/day       
0-10 0.56 0.34-0.93 0.02 0.53 0.27-0.63 0.04
21-30 0.90 0.64-1.27 0.55 0.74 0.48-1.14 0.18
>30 1.34 0.81-2.20 0.25 0.97 0.48-1.96 0.94
FTND (6 vs. 3 points) 1.09 1.03-1.16 0.01 1.09 0.98-1.21 0.12
Intensity of craving (VAS 100 vs. 50) 1.00 0.99-1.01 0.35 1.00 0.99-1.00 0.50
Exhaled CO, ppb 1.07 0.99-1.02 0.11 0.99 0.99-1.01 0.84
Motivation to quit (VAS 100 vs.50) 1.00 0.99-1.01 0.48 1.00 0.99-1.02 0.63
Motivation for smoking       
Weight control 1.10 0.79-1.55 0.57 1.02 0.65-1.59 0.94
Dependency 0.91 0.60-1.38 0.66 0.91 0.61-1.38 0.66
Mood control 1.32 0.93-1.86 0.12 0.97 0.63-1.48 0.87
Boredom 1.50 1.13-1.99 <0.01 1.68 1.21-2.33 <0.01
Unwillingness to quit 1.40 1.02-1.92 0.04 1.25 0.84-1.84 0.27
Relaxation 1.02 0.76-1.36 0.92 0.90 0.62-1.31 0.60
Obstipation 1.12 0.70-1.78 0.64 0.92 0.49-1.71 0.79
Pharmacological support       
Counselling only ---- ---- ----   --- ---
NRT       
Mono 0.82 0.41-1.68 0.59 --- --- ---
Combined 1.09 0.57-2.1 0.80 --- --- ---
Mono + bupropion 0.99 0.50-1.97 0.98 --- --- ---
Combined + bupropion 1.75 0.95-3.19 0.07 --- --- ---
Bupropion 1.43 0.68-3.02 0.34 --- --- ---
  1. The reference category for discontinuous or ordinal variables is given in parentheses. For continuous or ordinal variables, OR had to be based on meaningful differences of the predicting variable. BMI = Body mass index; FTND = Fagerstroem test for nicotine dependence; exhaled CO = exhaled carbon monoxide; NRT = Nicotine replacement therapy