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Table 2 Univariate and multivariate cox- regression analysis to predict postcessational weight gain of more than 5 % of baseline body weight within 24 months (n = 654)

From: Predictors of marked weight gain in a population of health care and industrial workers following smoking cessation

n = 654

 

Univariate cox -regression analysis

  

Multivariate cox-regression analysis

 

Variables

HR

95 % CI

p

HR

95 % CI

p

Demographics

      

Age (30 vs. 50 years)

1.00

0.99-1.02

0.59

1.00

0.97-1.03

0.94

BMI (20 vs. 30)

0.45

0.35-0.85

0.02

0.60

0.40-0.80

0.03

Gender

      

Male

----

----

----

---

---

---

Female

1.42

1.07-1.87

0.01

1.40

0.93-2.10

0.11

Civil status

      

Single)

----

----

----

---

---

---

Married

0.97

0.64-1.46

0.88

---

---

---

Divorced

0.78

0.44-1.39

0.46

---

---

---

Widowed

1.40

0.46-4.17

0.55

---

---

---

Education

      

University

----

----

----

---

---

---

Apprenticeship

1.97

1.20-3.24

<0.01

2.60

1.60-5.50

<0.01

Basic education

3.02

1.60-5.36

<0.01

2.90

1.39-4.83

<0.01

Comorbidities

      

Arterial Hypertension

0.99

0.52-1.91

1.00

1.05

0.51-2.18

0.89

Coronary heart disease

0.34

0.12-0.95

0.02

0.21

0.07-0.62

<0.01

Diabetes mellitus

2.22

1.11-6.01

0.04

3.05

2.20-8.06

0.02

Malignancy

1.01

0.44-2.32

0.98

0.61

0.25-1.50

0.28

Epilepsy

1.08

0.78-1.86

0.78

1.42

0.5-1.32

0.45

Antidepressant medication

0.93

0.62-1.40

0.73

0.89

0.54-1.46

0.64

Psychiatric disorder

1.19

0.78-1.80

0.41

1.07

0.62-1.85

0.79

Satisfaction with Life (Qol), (points)

0.98

0.95-1.01

0.26

0.98

0.95-1.02

0.42

Respiratory Symptoms

      

Cough

1.02

0.99-1.04

0.18

1.00

0.90-1.08

0.42

Sputum

1.50

1.08-2.07

0.01

1.32

0.89-1.95

0.17

Wheezing

1.23

1.10-2.34

0.26

1.31

1.09-1.17

0.35

Breathlessness at rest

1.59

0.94-2.69

0.09

1.29

0.65-2.55

0.47

Breathlessness at exertion

1.04

0.78-1.37

0.80

0.93

0.66-1.30

0.66

Smoking related history

      

Number of cigarettes/day

      

0-10

0.56

0.34-0.93

0.02

0.53

0.27-0.63

0.04

21-30

0.90

0.64-1.27

0.55

0.74

0.48-1.14

0.18

>30

1.34

0.81-2.20

0.25

0.97

0.48-1.96

0.94

FTND (6 vs. 3 points)

1.09

1.03-1.16

0.01

1.09

0.98-1.21

0.12

Intensity of craving (VAS 100 vs. 50)

1.00

0.99-1.01

0.35

1.00

0.99-1.00

0.50

Exhaled CO, ppb

1.07

0.99-1.02

0.11

0.99

0.99-1.01

0.84

Motivation to quit (VAS 100 vs.50)

1.00

0.99-1.01

0.48

1.00

0.99-1.02

0.63

Motivation for smoking

      

Weight control

1.10

0.79-1.55

0.57

1.02

0.65-1.59

0.94

Dependency

0.91

0.60-1.38

0.66

0.91

0.61-1.38

0.66

Mood control

1.32

0.93-1.86

0.12

0.97

0.63-1.48

0.87

Boredom

1.50

1.13-1.99

<0.01

1.68

1.21-2.33

<0.01

Unwillingness to quit

1.40

1.02-1.92

0.04

1.25

0.84-1.84

0.27

Relaxation

1.02

0.76-1.36

0.92

0.90

0.62-1.31

0.60

Obstipation

1.12

0.70-1.78

0.64

0.92

0.49-1.71

0.79

Pharmacological support

      

Counselling only

----

----

----

 

---

---

NRT

      

Mono

0.82

0.41-1.68

0.59

---

---

---

Combined

1.09

0.57-2.1

0.80

---

---

---

Mono + bupropion

0.99

0.50-1.97

0.98

---

---

---

Combined + bupropion

1.75

0.95-3.19

0.07

---

---

---

Bupropion

1.43

0.68-3.02

0.34

---

---

---

  1. The reference category for discontinuous or ordinal variables is given in parentheses. For continuous or ordinal variables, OR had to be based on meaningful differences of the predicting variable. BMI = Body mass index; FTND = Fagerstroem test for nicotine dependence; exhaled CO = exhaled carbon monoxide; NRT = Nicotine replacement therapy