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Table 2 Weibull univariable and multivariable analysis for predictors of time to attrition (lost to follow up and death) among adults initiated antiretroviral care in a rural HIV clinic in Coastal Kenya (N = 928)

From: Incidence and predictors of attrition from antiretroviral care among adults in a rural HIV clinic in Coastal Kenya: a retrospective cohort study

  Univariable Regression Multivariable regression (n = 761)
Characteristics Categories Attrition, n = 308 (n/100 pyo [rate]) Crude HR 95% CI LRT p-value Adjusted HR 95% CI LRT p-value
Gender Female 208/9.92 [21.0] 1.0 (Reference)   1.0 (Reference)  
Male 100/3.44 [29.1] 1.3 1.1 – 1.7 0.018 1.5 1.1 – 2.0 0.014
Age group (years) 15 – 24 38/1.24 [30.6] 1.5 1.0 – 2.2   2.2 1.3 – 3.7  
25 – 34 103/4.59 [22.4] 1.1 0.8 – 1.6   1.4 0.9 – 2.1  
35 – 44 112/4.74 [23.6] 1.2 0.9 – 1.6   1.3 0.9 – 2.0  
≥45 55/2.78 [19.8] 1.0 (Reference) 0.318 1.0 (Reference) 0.034
*Marital status Single 28/0.97 [29.0] 1.0 (Reference)
Married, Monogamous 128/5.69 [22.5] 0.8 0.5 – 1.2
Married, Polygamous 48/2.39 [20.1] 0.7 0.4 – 1.1
Separated/Divorced/Widowed 103/4.29 [24.0] 0.8 0.5 – 1.3 0.548
*Religion Christian 188/8.02 [23.4] 1.0 (Reference)
Muslim 55/2.37 [23.3] 1.0 0.7 – 1.4
Others 60/2.83 [21.2] 0.9 0.7 – 1.2 0.859
*Education No formal education 104/4.59 [22.6] 1.0 (Reference)
Primary education 144/6.02 [23.9] 1.0 0.8 – 1.3
Secondary/Higher education 54/2.61 [20.7] 0.9 0.6 – 1.2 0.608
*Distance from hospital (km) 0 – 5 119/5.0 [23.7] 1.0 (Reference)
5 – 10 57/3.2 [18.1] 0.8 0.6 – 1.1
≥10 82/3.9 [21.2] 0.9 0.7 – 1.2 0.270
Pre-ART duration (months) <12 207/8.6 [24.0] 1.0 (Reference)
12 – 36 68/3.2 [20.9] 0.9 0.7 – 1.2
≥36 33/1.5 [22.1] 0.9 0.6 – 1.4 0.663
*Baseline WHO clinical staging Stage I/II 141/8.13 [17.4] 1.0 (Reference) 1.0
Stage III/IV 124/5.05 [24.5] 1.4 1.1 – 1.8 0.009 1.1 0.8 – 1.5 0.527
*Baseline BMI (Kg/m2) <16.0 41/1.12 [36.7] 2.1 1.5 – 2.9   1.6 1.0 – 2.4  
16.0 – 18.5 72/3.53 [20.4] 1.2 0.9 – 1.6   1.0 0.7 – 1.4  
≥18.5 128/7.58 [16.9] 1.0 (Reference) <0.001 1.0 (Reference) 0.110
Baseline CD4 (cells/uL) 0 – 100 70/2.50 [28.0] 1.0 (Reference)   1.0 (Reference)  
100 – 350 54/4.46 [12.1] 0.5 0.3 – 0.7   0.5 0.3 – 0.7  
≥350 15/0.66 [22.6] 0.8 0.5 – 1.4   0.8 0.4 – 1.5  
Missing 169/5.74 [29.4] 1.1 0.8 – 1.4 <0.001 0.7 0.5 – 1.0 0.002
  1. ART (Antiretroviral therapy), BMI (Body Mass Index), LRT (Likelihood Ratio Test), pyo (person years of observation), WHO (World Health Organization).
  2. *Participants excluded from Weibull regression analysis (n = 167) due to missing marital status (n = 2), religion (n = 10), education status (n = 9), distance from hospital (n = 115), baseline WHO clinical staging (n = 59) and/or BMI (n = 123) data.