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Table 2 Weibull univariable and multivariable analysis for predictors of time to attrition (lost to follow up and death) among adults initiated antiretroviral care in a rural HIV clinic in Coastal Kenya (N = 928)

From: Incidence and predictors of attrition from antiretroviral care among adults in a rural HIV clinic in Coastal Kenya: a retrospective cohort study

 

Univariable Regression

Multivariable regression (n = 761)

Characteristics

Categories

Attrition, n = 308 (n/100 pyo [rate])

Crude HR

95% CI

LRT p-value

Adjusted HR

95% CI

LRT p-value

Gender

Female

208/9.92 [21.0]

1.0

(Reference)

 

1.0

(Reference)

 

Male

100/3.44 [29.1]

1.3

1.1 – 1.7

0.018

1.5

1.1 – 2.0

0.014

Age group (years)

15 – 24

38/1.24 [30.6]

1.5

1.0 – 2.2

 

2.2

1.3 – 3.7

 

25 – 34

103/4.59 [22.4]

1.1

0.8 – 1.6

 

1.4

0.9 – 2.1

 

35 – 44

112/4.74 [23.6]

1.2

0.9 – 1.6

 

1.3

0.9 – 2.0

 

≥45

55/2.78 [19.8]

1.0

(Reference)

0.318

1.0

(Reference)

0.034

*Marital status

Single

28/0.97 [29.0]

1.0

(Reference)

Married, Monogamous

128/5.69 [22.5]

0.8

0.5 – 1.2

Married, Polygamous

48/2.39 [20.1]

0.7

0.4 – 1.1

Separated/Divorced/Widowed

103/4.29 [24.0]

0.8

0.5 – 1.3

0.548

*Religion

Christian

188/8.02 [23.4]

1.0

(Reference)

Muslim

55/2.37 [23.3]

1.0

0.7 – 1.4

Others

60/2.83 [21.2]

0.9

0.7 – 1.2

0.859

*Education

No formal education

104/4.59 [22.6]

1.0

(Reference)

Primary education

144/6.02 [23.9]

1.0

0.8 – 1.3

Secondary/Higher education

54/2.61 [20.7]

0.9

0.6 – 1.2

0.608

*Distance from hospital (km)

0 – 5

119/5.0 [23.7]

1.0

(Reference)

5 – 10

57/3.2 [18.1]

0.8

0.6 – 1.1

≥10

82/3.9 [21.2]

0.9

0.7 – 1.2

0.270

Pre-ART duration (months)

<12

207/8.6 [24.0]

1.0

(Reference)

12 – 36

68/3.2 [20.9]

0.9

0.7 – 1.2

≥36

33/1.5 [22.1]

0.9

0.6 – 1.4

0.663

*Baseline WHO clinical staging

Stage I/II

141/8.13 [17.4]

1.0

(Reference)

1.0

Stage III/IV

124/5.05 [24.5]

1.4

1.1 – 1.8

0.009

1.1

0.8 – 1.5

0.527

*Baseline BMI (Kg/m2)

<16.0

41/1.12 [36.7]

2.1

1.5 – 2.9

 

1.6

1.0 – 2.4

 

16.0 – 18.5

72/3.53 [20.4]

1.2

0.9 – 1.6

 

1.0

0.7 – 1.4

 

≥18.5

128/7.58 [16.9]

1.0

(Reference)

<0.001

1.0

(Reference)

0.110

Baseline CD4 (cells/uL)

0 – 100

70/2.50 [28.0]

1.0

(Reference)

 

1.0

(Reference)

 

100 – 350

54/4.46 [12.1]

0.5

0.3 – 0.7

 

0.5

0.3 – 0.7

 

≥350

15/0.66 [22.6]

0.8

0.5 – 1.4

 

0.8

0.4 – 1.5

 

Missing

169/5.74 [29.4]

1.1

0.8 – 1.4

<0.001

0.7

0.5 – 1.0

0.002

  1. ART (Antiretroviral therapy), BMI (Body Mass Index), LRT (Likelihood Ratio Test), pyo (person years of observation), WHO (World Health Organization).
  2. *Participants excluded from Weibull regression analysis (n = 167) due to missing marital status (n = 2), religion (n = 10), education status (n = 9), distance from hospital (n = 115), baseline WHO clinical staging (n = 59) and/or BMI (n = 123) data.