Table 3 Hazard ratio of LTF and death after ART initiation

Age category

15-24 yrs

1

reference

1

reference

1

reference

1

reference

25-39 yrs

0.78

0.72-0.85

0.77

0.72-0.83

1.2

1.10-1.30

1.11

1.02-1.21

40-49 yrs

0.70

0.62-0.79

0.67

0.60-0.75

1.39

1.25-1.55

1.30

1.14-1.48

50+ yrs

0.74

0.60-0.91

0.67

0.54-0.81

1.54

1.38-1.73

1.61

1.42-1.83

Sex

Male

1

reference

1

reference

1

reference

1

reference

Female

0.79

0.75-0.83

0.73

0.70-0.76

0.71

0.66-0.77

0.90

0.82-0.98

Religion

Orthodox

1

reference

1

reference

1

reference

1

reference

Muslim

1.22

1.00-1.48

1.17

1.01-1.35

1.03

0.89-1.19

0.98

0.86-1.13

Protestant

0.89

0.72-1.11

0.99

0.88-1.10

0.84

0.70-1.00

0.77

0.69-0.86

Other/Unknown

1.20

1.01-1.43

0.91

0.80-1.03

1.15

0.87-1.53

0.88

0.70-1.10

Marital status

Never Married

1

reference

1

reference

1

reference

1

reference

Married/Living together

0.63

0.58-0.67

0.67

0.63-0.71

0.8

0.68-0.95

0.84

0.75-0.95

Separated/Divorced

0.83

0.77-0.89

0.90

0.84-0.96

0.92

0.78-1.09

1.02

0.87-1.19

Widowed

0.68

0.63-0.73

0.78

0.71-0.86

0.76

0.66-0.88

0.92

0.79-1.06

Other/Unknown

1.04

0.78-1.39

0.97

0.80-1.03

1.12

0.73-1.72

1.08

0.88-1.33

Education

No Education

1

reference

1

reference

1

reference

1

reference

Primary

0.74

0.70-0.79

0.71

0.66-0.75

1.23

1.16-1.29

1.27

1.18-1.36

Secondary

0.64

0.58-0.71

0.59

0.53-0.66

1.47

1.33-1.62

1.51

1.38-1.66

Tertiary

0.53

0.47-0.59

0.48

0.42-0.55

1.43

1.24-1.66

1.57

1.38-177

Other/Unknown

1.04

0.80-1.36

0.96

0.79-1.17

1.60

1.16-2.23

1.36

1.05-1.75

WHO Stage at ART initiation

Stage I

1

reference

1

reference

1

reference

1

reference

Stage II

0.96

0.86-1.07

0.94

0.85-1.04

1.15

0.96-1.38

1.07

0.89-1.27

Stage III

1.30

1.15-1.47

1.19

1.07-1.32

2.06

1.70-2.49

1.68

1.41-1.99

Stage IV

1.80

1.48-2.18

1.60

1.38-1.85

4.25

3.26-5.52

2.98

2.32-3.84

Missing

1.28

1.12-1.47

1.18

1.07-1.33

2.3

1.69-3.11

1.66

1.22-2.24

CD4+ cell count (cells/mm ³ ) at ART initiation

<100

1.39

1.18-1.64

1.43

1.20-1.71

1.62

1.27-2.06

1.84

1.37-2.46

100-199

0.97

0.82-1.16

1.09

0.91-1.31

0.75

0.57-0.98

1.01

0.74-1.37

200-350

0.87

0.72-1.04

0.96

0.78-1.19

0.48

0.37-0.62

0.64

0.49-0.85

350+

1

reference

1

reference

1

reference

1

reference

Missing

1.36

1.09-1.70

1.46

1.20-1.77

1.67

1.26-2.21

1.81

1.36-2.41

First ART regimen

D4T-containing regimen

1

reference

1

reference

1

reference

1

reference

AZT-containing regimen

0.86

0.75-0.98

0.76

0.67-0.85

0.75

0.64-0.88

0.79

0.69-0.91

TDF-containing regimen

0.92

0.81-1.04

0.66

0.59-0.74

0.60

0.51-0.70

0.74

0.64-0.86

Other

2.91

2.08-3.78

2.72

2.07-3.58

1.35

0.79-2.30

1.51

0.81-2.81

Change of ART regimen

0.26

0.21-0.32

0.25

0.19-0.31

0.48

0.42-0.56

0.41

0.35-0.49

Enrollment year

2006-2007

1

reference

1

reference

1

reference

1

reference

2008-2009

1.05

0.96-1.14

1.05

0.95-1.14

0.58

0.49-0.69

0.69

0.60-0.78

2010-2011

1.15

1.00-1.33

1.27

1.15-1.40

0.67

0.62-0.74

0.62

0.50-0.75

Point of entry

PITC

1.33

1.24-1.41

1.25

1.20-1.31

1.19

1.05-1.35

1.05

0.92-1.19

VCT

1

reference

1

reference

1

reference

Other Hospital/HC

1.19

1.08-1.30

1.12

1.05-1.20

0.89

0.78-1.03

0.83

0.72-0.95

Community

1.42

1.23-1.63

1.18

1.06-1.30

0.56

0.24-1.31

0.59

0.30-1.14

Unknown/missing

1.20

1.07-1.34

1.10

1.01-1.19

1.08

0.90-1.30

1.14

1.05-1.24

Facility type

Primary

0.67

0.49-0.92

0.86

0.60-1.24

1.03

0.63-1.69

1.28

0.77-2.14

Secondary/tertiary

1

reference

1

reference

1

reference

1

reference

Setting

Urban city (25 sites)

1

reference

1

reference

1

reference

1

reference

Semi-urban (21 sites)

0.93

0.71-1.21

0.89

0.72-1.09

1.33

0.87-2.05

1.36

0.86-2.16

Rural(10 sites)

0.67

0.49-0.92

0.66

0.51-0.85

2.06

1.35-3.16

1.92

1.16-3.18

CD4 testing on-site

1.47

1.18-1.83

1.31

1.08-1.60

0.68

0.48-0.96

0.85

0.62-1.06