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Table 2 Adult patient characteristics at ART initiation, by enrollment year

From: Characteristics and outcomes of adult Ethiopian patients enrolled in HIV care and treatment: a multi-clinic observational study

  Total 2006-2007 2008-2009 2010-2011 p-value1
  n = 53,300 %2 n = 21,920 %2 n = 19,296 %2 n = 12,084 %2
Age category          <0.0001
15-24 yrs 6,040 11.3 2425 11.1 2191 11.4 1,424 11.8  
25-39 yrs 33,303 62.5 13901 63.4 12031 62.4 7,371 61.0  
40-49 yrs 9,722 18.2 4045 18.5 3453 17.9 2,224 18.4  
50+ yrs 4,235 8.0 1549 7.1 1621 8.4 1,065 8.8  
Sex          0.14
Male 22,302 41.8 9284 42.4 8004 41.5 5,014 41.5  
Female 30,998 58.2 12636 57.7 11292 58.5 7,070 58.5  
WHO Stage at ART initiation         <0.0001
Stage I 7,516 14.1 1830 8.3 3246 16.8 2,440 20.2  
Stage II 10,890 20.4 4002 18.3 4297 22.3 2,591 21.4  
Stage III 27,930 52.4 12403 56.6 9769 50.6 5,758 47.6  
Stage IV 5,894 11.1 3284 15.0 1580 8.2 1,030 8.5  
Missing 1,070 2.0 401 1.8 404 2.1 265 2.2  
CD4+ cell count, cells/mm 3 at ART initiation        
Median (IQR) 132 (68–197) 128 (66–192) 137 (71–201) 132 (65–202) <0.0001
<100 18,227 34.2 7,816 35.7 6,247 32.4 4,164 34.5  
100-199 18,596 34.9 7,927 36.2 6,696 34.7 3,973 32.9  
200-350 10,829 20.3 4,063 18.5 4,121 21.4 2,645 21.9  
350+ 935 1.8 409 1.9 309 1.6 217 1.8  
Missing 4,713 8.8 1,705 7.8 1,923 10.0 1,085 9.0  
First ART regimen          <0.0001
D4T-containing regimen 27,380 51.4 15,318 69.9 11,100 57.5 962 8.0  
AZT-containing regimen 13,509 25.4 5,733 26.2 5,159 26.7 2,617 21.7  
TDF-containing regimen 12,124 22.8 846 3.9 2,840 14.7 8,438 69.8  
Other 287 0.5 23 0.1 197 1.0 67 0.6  
Facility type          <0.0001
Primary (11 sites) 2,421 4.5 712 3.3 906 4.7 803 6.7  
Secondary/Tertiary (45 sites) 50,879 95.5 21,208 96.8 18,390 95.3 11,281 93.4  
Setting          
Urban city (25 sites) 33,491 62.8 14,498 66.1 11,705 60.7 7,288 60.3 <0.0001
Semi-urban (21 sites) 16,711 31.4 6,616 30.2 6,435 33.4 3,660 30.3  
Rural (10 sites) 3,098 5.8 806 3.7 1,156 6.0 1,136 9.4  
CD4 testing performed on-site         
Yes 44,353 83.2 18,699 85.3 15,889 82.3 9,765 80.8 <0.0001
No 8,947 16.8 3,221 14.7 3,407 17.7 2,319 19.2  
  1. 1p-values based on chi-squared test for any difference across groups over time. see text for specific tests for trend.
  2. 2 categorical percentages may not total exactly 100% due to roundoff errors.