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Table 2 Adult patient characteristics at ART initiation, by enrollment year

From: Characteristics and outcomes of adult Ethiopian patients enrolled in HIV care and treatment: a multi-clinic observational study

 

Total

2006-2007

2008-2009

2010-2011

p-value1

 

n = 53,300

%2

n = 21,920

%2

n = 19,296

%2

n = 12,084

%2

Age category

        

<0.0001

15-24 yrs

6,040

11.3

2425

11.1

2191

11.4

1,424

11.8

 

25-39 yrs

33,303

62.5

13901

63.4

12031

62.4

7,371

61.0

 

40-49 yrs

9,722

18.2

4045

18.5

3453

17.9

2,224

18.4

 

50+ yrs

4,235

8.0

1549

7.1

1621

8.4

1,065

8.8

 

Sex

        

0.14

Male

22,302

41.8

9284

42.4

8004

41.5

5,014

41.5

 

Female

30,998

58.2

12636

57.7

11292

58.5

7,070

58.5

 

WHO Stage at ART initiation

       

<0.0001

Stage I

7,516

14.1

1830

8.3

3246

16.8

2,440

20.2

 

Stage II

10,890

20.4

4002

18.3

4297

22.3

2,591

21.4

 

Stage III

27,930

52.4

12403

56.6

9769

50.6

5,758

47.6

 

Stage IV

5,894

11.1

3284

15.0

1580

8.2

1,030

8.5

 

Missing

1,070

2.0

401

1.8

404

2.1

265

2.2

 

CD4+ cell count, cells/mm 3 at ART initiation

       

Median (IQR)

132 (68–197)

128 (66–192)

137 (71–201)

132 (65–202)

<0.0001

<100

18,227

34.2

7,816

35.7

6,247

32.4

4,164

34.5

 

100-199

18,596

34.9

7,927

36.2

6,696

34.7

3,973

32.9

 

200-350

10,829

20.3

4,063

18.5

4,121

21.4

2,645

21.9

 

350+

935

1.8

409

1.9

309

1.6

217

1.8

 

Missing

4,713

8.8

1,705

7.8

1,923

10.0

1,085

9.0

 

First ART regimen

        

<0.0001

D4T-containing regimen

27,380

51.4

15,318

69.9

11,100

57.5

962

8.0

 

AZT-containing regimen

13,509

25.4

5,733

26.2

5,159

26.7

2,617

21.7

 

TDF-containing regimen

12,124

22.8

846

3.9

2,840

14.7

8,438

69.8

 

Other

287

0.5

23

0.1

197

1.0

67

0.6

 

Facility type

        

<0.0001

Primary (11 sites)

2,421

4.5

712

3.3

906

4.7

803

6.7

 

Secondary/Tertiary (45 sites)

50,879

95.5

21,208

96.8

18,390

95.3

11,281

93.4

 

Setting

         

Urban city (25 sites)

33,491

62.8

14,498

66.1

11,705

60.7

7,288

60.3

<0.0001

Semi-urban (21 sites)

16,711

31.4

6,616

30.2

6,435

33.4

3,660

30.3

 

Rural (10 sites)

3,098

5.8

806

3.7

1,156

6.0

1,136

9.4

 

CD4 testing performed on-site

        

Yes

44,353

83.2

18,699

85.3

15,889

82.3

9,765

80.8

<0.0001

No

8,947

16.8

3,221

14.7

3,407

17.7

2,319

19.2

 
  1. 1p-values based on chi-squared test for any difference across groups over time. see text for specific tests for trend.
  2. 2 categorical percentages may not total exactly 100% due to roundoff errors.
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