The prospective association between obesity and major depression in the general population: does single or recurrent episode matter?

Table 2 Baseline BMI/obesity and rate of MDD-S/MDD-R at follow-up (N = 964)

Parameter	Major depressive disorder (MDD)
Parameter	MDD-S OR (95%CI) (N = 772) ^a	MDD-R OR (95%CI) (N = 886) ^b
Body Mass Index (BMI)
Crude model	0.97 (0.88; 1.07)	1.36 (1.17; 1.59)
Adjusted Model^c	0.98 (0.89; 1.07)	1.32 (1.11; 1.57)
Obesity (BMI ≥ 30 kg/m2)
Non obese	Ref.	Ref.
Obese (Crude)	0.75 (0.26; 2.20)	15.17 (1.57; 146.98)
Obese (adjusted)^c	0.75 (0.25; 2.30)	11.63 (1.05; 128.60)

OR: odds ratio; CI: confidence interval; OR of BMI represent the effect of an increase of ‘1’ of the BMI; ; MDD-S/MDD-R, major depressive disorder- single/recurrent episode; ^aDuring prospective analyses, 192/964 (20%) individuals with a lifetime diagnosis of MDD-S/MDD-R at baseline were excluded; ^b78/964 (8%) individuals with MDD-R at baseline were excluded during analysis. ^cAdjusted for age, sex, marital status, education, exercise and smoking status.

ISSN: 1471-2458