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Table 1 Characteristics of studies included in the review of variation of M/DR-TB in SSA; 2003–2013

From: Variation and risk factors of drug resistant tuberculosis in sub-Saharan Africa: a systematic review and meta-analysis

Author

Study year

Country

Study description

Patient category

Sample size (included in DST)

HIV prevalence in the study (%)

Country HIV prevalence (%)

DST method

Type of resistance tested

Minime-Lingoupou F et al. [21]

2009

Central African Republic

Sub-national survey. TB health facilities in Bangui and Bimbo.

New patients

233

26

N/A

LJ

INH, RMP, SM, EMB

Asmamaw D. et al. [22]

2004

Ethiopia

Sub-national survey. Twenty-four TB health facilities in Addis Ababa.

New patients

231

29.6

2.9

LJ

INH, RMP, SM, EMB

Abdelhadi O. et al. [23]

2009-2010

Chad

Sub-national survey. Number of TB facilities not provided.

New patients

135

25

3

LJ

INH, RMP, SM, EMB

Yimer S.A. et al. [24]

2008

Ethiopia

Sub-national survey. Number of TB facilities in Amhara not provided.

New patients

112

26.9

1.9

MGIT

INH, RMP, SM, EMB

Urassa W. et al. [25]

2001-2004

Tanzania

Sub-national survey. Five TB health facilities in Dar es Salaam.

New patients

887

53

5.7

LJ

INH, RMP, SM, EMB

Ndungu PW. et al. [26]

2010

Kenya

Sub-national survey. Five TB health facilities in and around Nairobi.

New patients

356

26.3

6.6

MGIT/LJ

INH, RMP, SM, EMB

Matee M. et al. [27]

2005-2006

Tanzania

Sub-national survey: Thirty-seven TB facilities of Temeke district.

New patients

226

N/A

5.8

LJ

INH, RMP, SM, EMB

Lukoye D. et al. (a) [28]

2008

Uganda

Sub-national survey. Twenty-two TB health facilities in Kampala.

New and PT patients

557

30.9

6.7

LJ

INH, RMP, SM, EMB. Km and O

Sanders M. et al. [29]

2008

Burundi

Sub-national survey. Seven TB health facilities in Bujumbura.

New and PT patients

859

N/A

2.2

LJ

INH, RMP, SM, EMB, PABA

Lukoye D. et al. (b) [30]

2009-2011

Uganda

National survey.

New and PT patients

1537

30.7

7.3

LJ

INH, RMP, SM, EMB, KM and OFX

Umubyeyi A. N. et al. [31]

2004-2005

Rwanda

National survey.

New and PT patients

701

N/A

3.3

LJ

INH, RMP, SM, EMB

Irenious S. et al.[15]

2011

Somalia

National survey.

New and PT patients

946

N/A

N/A

Hain

INH, RMP only

Chonde TM et al.[32]

2006-2007

Tanzania

National survey.

New and PT patients

1,167

N/A

5.8

LJ

INH, RMP, SM, EMB

Tessema B. et al.[33]

2009

Ethiopia

Sub-national survey. Five TB health facilities in north west Ethiopia.

New and PT patients

260

25.4

1.7

LJ

INH, RMP, SM, EMB, CPM, OFX, AM, MFX, Amino Salicylic Acid

Chanda M. et al. [34]

2006

Zambia

Sub-national survey. Six TB health facilities in Ndola district.

New and PT patients

361

N/A

13.2

LJ

INH, RMP, SM, EMB

Nunes E.A. et al. [35]

2002-2003

Mozambique

Sub-national survey. Number of TB health facilities not provided.

New and PT patients

111

N/A

9.8

LJ

INH, RMP, SM, EMB

Nelson L.J. et al. [36]

2002

Botswana

National survey.

New and PT patients

2,425

60

25.7

LJ

INH, RMP, SM, EMB

Ramarokoto H. et al.[37]

2005-2007

Madagascar

National survey.

New and PT patients

1,275

N/A

0.6

LJ

INH, RMP, SM, EMB

Samo Gudo P. et al. [38]

2007-2008

Mozambique

National survey.

New and PT patients

1,200

N/A

11.5

LJ

INH, RMP, SM, EMB

Sanchez-Padilla E. et al.

2009

Swaziland

National survey

New and PT patients

633

79.9

25.8

MGIT or LJ

INH, RMP, SM, EMB

Edgbola R.A. et al. [39]

1999

Gambia

National survey.

New and PT patients

225

N/A

2.1

LJ

INH, RMP, SM, EMB

Affolabi D. et al. [40]

2002-2004

Benin

Sub-national survey. National Pneumo-Phthisiology hospita receiving patients from Benin and surrounding countries

New and PT patients

470

10.2

2.3

LJ

INH, RMP, SM, EMB

Tudo G. et al. [41]

2004

Equatorial Guinea

Sub-national survey. Number of TB health facilities not provided.

New and PT patients

236

13.5

3.6

LJ

INH, RMP, SM, EMB

N'guesesan K. et al.[42]

2005

Ivory Coast

National survey.

New patients

320

N/A

4.9

LJ

INH, RMP, SM, EMB

Sangare L. et al. [43]

2010

Bukina Furso

National survey.

New and PT patients

416

28.7

1.3

LJ

INH, RMP, SM, EMB

Ellis Awusu-Dabo et al. [44]

2001-2004

Ghana

National survey.

New and PT patients

216

25.9

4.7

 

INH, RMP, SM, EMB, Thiacetazone

Jurgen Noesk et al. [45]

2012

Cameroon

Sub-national. Twenty-nine TB health facilities in Litoral region.

PT patients

233

26

N/A

LJ

INH, RMP, SM, EMB, Km and GFX

Mbulo G.M.K. et al. Results of the national drug resistance survey in Zambia. (in preparation)

2008

Zambia

National survey.

New and PT patients

883

47.6

13.3

LJ

INH, RMP, SM, EMB

  1. Abbreviations: DST drug susceptibility testing, INH isoniazid, RMP rifampicin, EMB ethambutol, SM streptomycin, Km kanamycin, GFX gatifloxacin, CPM capreomycin, OFX ofloxacin, AM amikacin, N/A, not available, LJ Löwenstein Jensen, MGIT mycobacteria growth indicator tube, PT previously treated patient.