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Table 3 Ratio of dengue hemorrhagic fever to dengue fever (DHF:DF) at infection two in individuals with two symptomatic infections according to sequential serotype pair and serologic response at infection one

From: Sequential dengue virus infections detected in active and passive surveillance programs in Thailand, 1994–2010

Serotype at infection one

Serological response at infection one

DHF:DF ratio

Serotype at infection two

DENV-1

DENV-2

DENV-3

DENV-4

Anya

DENV-1

Primary

-

9.0 (9:1)

Ind. (4:0)

2.0 (8:4)

3.3 (23:7)

Secondary

-

1.2 (13:11)

1.3 (5:4)

0.6 (3:5)

1.3 (31:23)

Allb

-

1.8 (24:13)

2.3 (9:4)

1.1 (11:10)

1.7 (58:34)

DENV-2

Primary

2.0 (2:1)

-

Ind. (1:0)

1.0 (1:1)

2 (6:3)

Secondary

5.0 (5:1)

-

4.0 (4:1)

5.0 (5:1)

2.6 (21:8)

Allb

3.5 (7:2)

-

5.0 (5:1)

3.0 (6:2)

2.3 (27:12)

DENV-3

Primary

3.0 (3:1)

1.0 (2:2)

-

1.0 (1:1)

1.1 (9:8)

Secondary

2.0 (4:2)

3.5 (7:2)

-

0.6 (3:5)

1.6 (19:12)

Allb

2.3 (7:3)

2.3 (9:4)

-

0.7 (4:6)

1.4 (28:20)

DENV-4

Primary

-

-

-

-

-

Secondary

0.5 (1:2)

0.5 (1:2)

-

-

0.7 (4:6)

Allb

0.5 (1:2)

1.0 (2:2)

-

-

0.8 (5:6)

Anya

Primary

2.7 (8:3)

3.6 (18:5)

Ind. (6:0)

1.6 (11:7)

2.2 (55:25)

Secondary

1.2 (16:13)

1.7 (38:22)

1.1 (10:9)

1.2 (20:17)

1.4 (127:88)

Allb

1.5 (24:16)

2.3 (63:28)

1.8 (16:9)

1.3 (32:25)

1.6 (192:118)

  1. A total of 323 of 502 sequential dengue virus (DENV) infections were symptomatic at both infection one and two. Of these 323, 13 without DHF/DF classification at infection two (marked as DHF/hospitalized DF in Table 1) were not included in this table. Statistical power was limited by the small numbers within each cell.
  2. aIncludes any case captured regardless of knowing or not knowing the infecting serotype.
  3. bIncludes all cases captured regardless of serologic response at infection one. Therefore, ones with unknown response are also included.
  4. Ind = indeterminate.