Sequential dengue virus infections detected in active and passive surveillance programs in Thailand, 1994–2010

BMC Public Health

Table 2 Data of individuals with three detected infections

		Age at infection			Serotype^a			Serologic response^b			Clinical category^c
	Infection order	1	2	3	1	2	3	1	2	3	1	2	3
Indiv.	Titers > 10^d
1	0	8.7	12.8	14.9	ND	NEG	DEN4	ND	S	S	SubC/nhDF	DHF	DHF
2	0	8.9	10.9	12.2	ND	ND	ND	ND	ND	ND	SubC	SubC	SubC
3	ND	10.5	10.8	10.9	NEG	DEN1	NEG	S	S	S	nhDF/hDF	hDF	hDF
4	0	7.7	8.7	11.0	ND	ND	DEN2	ND	ND	S	SubC/nhDF	SubC/nhDF	nhDF
5	4	7.5	8.5	10.5	ND	ND	ND	ND	ND	ND	SubC	SubC	SubC
6	0	7.9	9.2	12.2	ND	ND	ND	ND	ND	ND	SubC/nhDF	SubC	SubC
7	0	7.9	9.4	12.8	DEN1	NEG	ND	S	S	ND	DHF	nhDF	SubC
8	4	9.0	12.3	12.9	ND	ND	DEN2	ND	ND	S	SubC	SubC	DHF
9	ND	5.9	9.3	10.2	NEG	ND	ND	S	ND	ND	DHF	SubC	SubC
10	4	7.8	9.0	10.3	ND	ND	ND	ND	ND	ND	SubC/nhDF	SubC	SubC
11	ND	9.1	11.1	11.8	DEN1	DEN3	ND	S	S	ND	hDF	nhDF	SubC/nhDF
12	0	7.8	10.8	12.3	ND	ND	ND	ND	ND	ND	SubC/nhDF	SubC/nhDF	SubC
13	0	7.8	8.8	10.1	ND	ND	DEN2	ND	ND	S	SubC/nhDF	SubC/nhDF	nhDF
14	ND	5.3	8.7	9.8	NEG	DEN2	ND	S	S	ND	DHF	nhDF	SubC

^aDengue virus (DENV) serotype detected by RT-PCR or viral culture. NEG = no virus detected. ND = RT-PCR not performed (no symptomatic infection occurred).
^bS = secondary response. ND = not determined (no symptomatic infection occurred).
^cSubC = subclinical DENV infection (captured by four-fold rise in dengue hemagglutination inhibition (HAI) titers without identified acute symptomatic DENV infection); SubC/nhDF = subclinical/non-hospitalized dengue fever (DF) (infections captured by four-fold rise in HAI titers outside the active study surveillance period; see Methods for detailed explanation); nhDF = non-hospitalized DF; hDF = hospitalized DF.
^dNumber of DENV serotypes with HAI titer >10 prior to infection one.

ISSN: 1471-2458