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Table 2 Hazard ratios of mortality according to baseline variables among MSM patients diagnosed with AIDS in Brazil, 19982008

From: Improvement of HAART in Brazil, 1998–2008: a nationwide assessment of survival times after AIDS diagnosis among men who have sex with men

 

Adjusted

Adjusted by state frailty effect

Predictor

HR

95% CI

HR

95% CI

Age (per 10 year increase)

1.13*

(1.11 - 1.16)

1. 13*

(1.11 - 1.16)

Race**

    

  White

Reference

  

Reference

  Non-white

1.15*

(1.09 - 1.21)

1.29*

(1.22 - 1.37)

  Unspecified

0.89*

(0.84 - 0.94)

1.02

(0.96 - 1.08)

Period of diagnosist

    

  1998-2001

Reference

  

Reference

  2002-2005

0.54*

(0.51 - 0.57)

0.55*

(0.52 - 0.58)

  2006-2008

0.51*

(0.48 - 0.55)

0.52*

(0.49 - 0.56)

CD4 cell count at diagnosis (cells/mm3)

    

  < 200

Reference

  

Reference

  200 - 350

0.65*

(0.63 - 0.68)

0.67*

(0.65 - 0.70)

  >350

0.20*

(0.18 - 0.21)

0.19*

(0.17 - 0.20)

HIV-1 RNA (log10 copies)

    

  <4.00

Reference

  

Reference

  4.00-5.00

1.28*

(1.19 - 1.37)

1.22*

(1.14 - 1.31)

  >5.00

4.68*

(4.40 - 4.98)

5.26*

(4.94 - 5.61)

Estimated frailty variance

 

---

 

0.099*

  1. Hazard Ratio (95% Confidence Interval); *p-value < 0.001; Cox proportional hazards model adjusted for all variables listed in the table. tComparing period of diagnosis in 2006–2008 to the reference of 2002–2005: adjusted HR: 0.95 (95% CI: 0.89 - 1.02; p = 0.144); model adjusted for state frailty effect: HR: 0.94 (95% CI: 0.88 - 0.01; p = 0.085).