From: Modeling the impact of tuberculosis interventions on epidemiologic outcomes and health system costs
Interventions | Specific parameter change1 | Primary active cases arising in cohort over 20 years3 | Total projected outcomes related to the primary cases | |||||
---|---|---|---|---|---|---|---|---|
 | Parameter | Pre | Post | Death during diagnosis and treatment phase | Cure due to treatment | Secondary cases generated from primary cases | Health system cost | |
Baseline | - | - | - | 69.82 | 47.34 | 2.40 | 106.05 | $2,818.01 |
Community Education | Patient delay2 | 11% | 6% | 69.82 | 45.97 | 2.51 | 104.24 | $2,955.56 |
DOTS expansion for diagnosis | Incorrect Diagnostic Test | 60% | 35% | 69.82 | 39.57 | 3.92 | 94.82 | $4,075.36 |
Diagnostic Delay2 | 8% | 0.5% | 69.82 | 46.29 | 2.54 | 104.44 | $2,942.14 | |
Loss to follow up during diagnosis | 25% | 14% | 69.82 | 45.47 | 2.76 | 103.35 | $3,121.12 | |
DOTS Expansion for Treatment | Incorrect Treatment | 79% | 13% | 69.82 | 47.34 | 10.00 | 99.21 | $2,920.66 |
Non specific DOTS Expansion (NTP Strengthening) | Access Government Facility | 94.5% | 97.5% | 69.82 | 46.96 | 2.47 | 105.50 | $2,906.57 |
HIV/ ART therapy programmes | HIV/TB Death rate | 12% | 10% | 69.82 | 47.34 | 2.45 | 106.05 | $2,818.01 |
HIV/TB Relapse rate | 16% | 1% | 69.82 | 47.34 | 2.70 | 105.93 | $2,818.01 | |
HIV/TB Reactivation rate | 3.4% | 2% | 57.11 | 39.55 | 2.01 | 86.58 | $2,326.66 | |
MDR-TB related interventions | DST performed | 20% | 50% | 69.82 | 47.34 | 2.41 | 106.02 | $2,986.38 |
Loss to follow up during MDR Treatment | 22% | 11% | 69.82 | 47.34 | 2.40 | 106.05 | $2,819.07 |