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Table 2 Frequencies of alleles and genotypes in rs16969968-, rs578776-, and rs12914008-tagging loci in the studied sample and in the HapMap CEU* reference population

From: Nicotine dependence in an isolated population of Kashubians from North Poland: a population survey

Polymorphism Allele/ genotype Frequency (%) pvalue
Kashubians(North Poland) HapMap CEU/Global MAF**
rs16969968 (CHRNA5) A 30.6 38.5 0.02
  G 69.4 61.5
  AA 9.7 15.9 0.04
  AG 41.8 45.1 0.50
  GG 48.5 38.9 0.05
rs578776 (CHRNA3) C 72.1 75.2 0.33
  T 27.9 24.8
  CC 51.7 56.6 0.32
  CT 40.9 37.2 0.45
  TT 7.4 6.2 0.63
rs12914008 (CHRNB4) A 4.6 3.3/1.7 0.68
  G 95.4 96.7
  AA 0.3 0 0.42
  AG 8.6 6.7 0.78
  GG 91.1 93.3 0.72
  1. *HapMap Data Release 27 Phase II + III, February 2009.
  2. **Global MAF in 1000 Genome Phase1 genotype data from 1094 worldwide individuals released in the May 2011 dataset.
  3. Values in boldface denote a significant association.