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Table 4 Difference in Vitamin D levels by asthma severity indicators in active asthmatics

From: Vitamin D levels and status amongst asthmatic and non-asthmatic adolescents in Cyprus: a comparative cross-sectional study

Asthma severity indicators Vitamin D Difference in mean Vitamin D levels between negative and positive response
Mean levels
Ng/mL (SD) (Reference Group: Negative) §
n = 69± b coefficient (95% CI); p value
Model 1* Model 2*
Asthma attacks in the last 12 months
No 59.4% 21.58 (5.54) −3.10 −3.05
Yes 40.6% 19.41 (5.40) (−5.80, −0.41); p = 0.03 (−6.07, −0.04); p = 0.05
Asthma medication use
No 62.3% 21.38 (5.31) −2.00 −1.80
Yes 37.7% 19.35 (5.78) (−4.92, 0.92); p = 0.18 (−4.82, 1.22); p = 0.24
Hospital admission
No 82.2% 21.07 (5.28) −2.90 −2.40
Yes 18.8% 18.52 (6.45) (−6.18, 0.67); p = 0.11 (−6.13, 1.34); p = 0.20
Emergency room visit
No 65.2% 21.77 (5.04) −3.43 −3.76
Yes 34.8% 18.72 (5.89) (−6.18, −0.67); p = 0.02 (−6.74, −0.79); p = 0.01
Asthma severity index
No Positive Answers 29.5% 22.62 (4.84) −1.51 −1.55
1 Positive Answer 26.2% 21.13 (5.57) (−2.64, −0.37); p = 0.01 (−2.78, −0.33); p = 0.01
2 Positive Answers 23.0% 19.75 (5.28)   
3 Positive Answers 16.4% 18.50 (6.18)   
4 Positive Answers 4.9% 16.43 (6.58)   
  1. Notes: §b coefficients correspond to difference in mean vitamin D levels as estimated in linear regression models. *Model 1adjusted for seasonality. Model 2 further adjusting for gender, family history of Allergies, body fat %, smoking status and parental education. ±Missing data ranged from 0–8. Change in mean vitamin D levels per 1 unit change in asthma severity index (i.e. across increasing categories of severity).