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Table 1 Basic maternal and perinatal characteristics of the study population in relation to asthma ever

From: Maternal socioeconomic status and the risk of asthma among offspring

Characteristics

No asthma N(%)

Asthma N(%)

pvalue

Maternal age, years

   

 <20

1246(3.3)

69(2.7)

 

 20-29

19 613(52.3)

1366(54.2)

 

 30-39

15 544(41.3)

1015(40.3)

 

 ≥40

1197(3.2)

68(2.7)

0.083

Maternal parity, primiparous

15 359(40.7)

967(38.4)

0.016

Maternal asthma

1016(2.7)

113(4.5)

<0.001

Maternal gestational diabetes mellitus

2619(7.0)

143(5.7)

0.014

Maternal hypertension

716(1.9)

74(2.9)

<0.001

Assisted reproduction technology, index pregnancy 1

1514(4.0)

142(5.6)

<0.001

Pre-pregnancy BMI*, kg/m 2

   

 <25

25 675(71.4)

1702(70.6)

 

 25-29.9

7105(19.8)

480(19.9)

 

 ≥30

3182(8.8)

228(9.5)

0.557

Marital status

   

Unmarried

3938(10.5)

274(10.9)

 

Married or cohabiting

33 662(89.5)

2244(89.1)

0.518

Socioeconomic status

   

Upper white-collar worker

5375(14.3)

359(14.3)

 

Lower white-collar worker

13 790(36.7)

973(38.6)

 

Blue-collar worker

7528(20.0)

477(18.9)

 

Entrepreneurs

1115(3.0)

52(2.1)

 

Other

7582(20.2)

543(21.6)

 

Missing

2210(5.9)

114(4.5)

0.001

Parental smoking**

   

Non-smoking parents

19 215(55.2)

1240(52.3)

 

Maternal/paternal smoking

8992(25.8)

633(26.7)

 

Both smoking parents

6620(19.0)

498(21.0)

0.013

Mode of delivery

   

 Vaginal

31 288(83.2)

2000(79.4)

 

 Cesarean delivery

6312(16.8)

518(20.6)

<0.001

Sex of child, boy

18 940(50.4)

1521(60.4)

<0.001

Gestational age at birth, weeks

   

 <28

129(0.3)

50(2.0)

 

 28-32

341(0.9)

80(3.2)

 

 33-36

1579(4.2)

149(5.9)

 

 37-40

26 253(69.8)

1724(68.5)

 

 ≥41

9298(24.7)

515(20.5)

<0.001

Birth weight <2500 grams

1482(3.9)

221(8.8)

<0.001

Small for gestational age (SGA)

13569(9.5)

263(10.4)

0.117

Asthma prevalence by age group, years

   

 1-6

13 251(35.2)

445(17.7)

 

 7-12

10 390(27.6)

945(37.5)

 

 ≥13

13 959(37.1)

1128(44.8)

<0.001

Mean age at the onset of asthma, years (±SD)

 

4.2(3.5)

 

Total study population

37600(93.7)

2518(6.3)

 
  1. 1Assisted reproduction technology before index pregnancy including in vitro fertilization, intra-cytoplasmic sperm injection, insemination and ovulation induction by clomifene citrate and other medicines.
  2. 2BMI: kilograms/square meters.
  3. *Body mass index, data missing 1746 (4.4%) cases.
  4. **Data missing 2920 (7.3%) cases.