Key research areas | Research questions | Home-based survey | Clinic-based survey | Community qualitative study | Costs assessment and time-motion survey | Health care professionals survey |
---|---|---|---|---|---|---|
Community perceptions and experiences | What are the community perceptions and experiences of the trial intervention package? | Â | Â | X | Â | Â |
How does the trial intervention package of HIV testing and care fit with community’s experience of Department of Health service provision? |  |  | X |  |  | |
Can communities be successfully engaged in the trial intervention package, i.e. does community stigma towards PLWHIV decrease and social support improve over the duration of the trial? | X | X | X | Â | Â | |
HIV testing | What are the individuals and community attitudes to and perceptions of HIV testing and repeat HIV testing, and do these change over the duration of the trial? | X | Â | X | Â | Â |
What are the social, economic and environmental barriers to initial and repeat home-based HIV testing, and do these change over duration of the trial? | X | Â | X | Â | Â | |
What is the impact of repeat HIV testing on disclosure and conjugal relationships and do these change over the duration of the trial? | Â | Â | Â | Â | Â | |
Linkage to HIV care | What are the social, economic and environmental barriers to entry into care and do these change over duration of the trial? | X | X | X | Â | Â |
How acceptable to individuals and the community is the trial model of HIV care? | Â | X | X | Â | Â | |
HIV care and treatment | What are community and individual expectations, perceptions and knowledge of immediate ART over time? | X | X | X | Â | Â |
What are the social, economic and environmental barriers to immediate ART and do these change over the duration of the trial? | Â | X | X | Â | Â | |
What is the impact of immediate ART on adherence and retention in care and how does it changes over time? | Â | X | X | Â | Â | |
What are the causal impacts of immediate ART for quality of life and patient satisfaction? | Â | X | Â | Â | Â | |
What are the psycho-social impacts (disclosure status, union-break up, social support, perceived stigma, depression, gender-based violence) of immediate ART? | Â | X | X | Â | Â | |
What are community and individual expectations, perceptions and knowledge of immediate ART and do these change over time? | X | X | X | Â | Â | |
Sexual behaviours and HIV risk/prevention practices | What are the most common HIV sexual risk behaviours and practices (e.g. multiple concurrent partners)? | X | X | Â | Â | Â |
What are the main prevention strategies (change in sexual practices, condom use, male circumcision) and do these changes over the duration of the trial? | X | X | Â | Â | Â | |
 | What are the effects of immediate ART on sexual behaviours and HIV prevention practices? | X | X |  |  |  |
Economic impacts and economic value | What is the causal impact of the trial intervention package on employment, household welfare and private health care spending? | X | X | Â | Â | Â |
How does the trial intervention affect quality of care and health systems outcomes, such as impacts on health care professionals (training, working conditions, practices, perceptions) and health care capacity? | Â | Â | Â | Â | X | |
What are the cost and the cost-effectiveness of the trial intervention package (home-based testing, immediate ART) in this rural South African context? What is the full social net value of the trial intervention package? | X | X | Â | X | X | |
What is the feasibility and financial sustainability (budget impact) of the trial intervention package (health system level) in this rural South African context? | X | X | Â | X | X |