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Table 2 Factors associated with second-line ARV prices

From: Factors influencing global antiretroviral procurement prices

Antiretroviral drugs+

ABC

300 mg

ddI

100 mg

ddI

400 mg

LPV/r

133/33 mg

RTV

100 mg

TDV

300 mg

HIV Prevalence 2-5%

-0.060

(-0.181, 0.061)

-0.109

(-0.298, 0.080)

-0.509**

(-0.663, -0.354)

-0.405*

(-0.785, -0.024)

-0.107

(-0.453, -0.239)

-0.126*

(-0.222, -0.031)

HIV Prevalence >5%

-0.092

(-0.247, 0.063)

-0.167

(-0.335, -0.002)

-0.343**

(-0.417, -0.269)

-0.629*

(-1.015, -0.244)

-0.382

(-1.041, 0.277)

-0.137*

(-0.265, 0.010)

Lower-middle-income

-0.018

(-0.155, 0.118)

0.227

(-0.417, 0.871)

0.573

(0.199, 0.948)

0.657

(0.033, 1.282)*

-0.050

(-0.328, 0.428)

0.165

(-0.006, 0.337)

Upper-middle-income

-0.040

(-0.278, 0.198)

0.407

(0.129, 0.684)*

0.369

(0.063, 0.676)*

0.284

(-0.373, 0.942)

-0.049

(-0.313, 0.410)

0.272*

(0.076, 0.467)

Volume 2nd tercile

-0.006

(-0.123, 0.111)

0.010

(-0.165, 0.185)

0.146

(-0.096, 0.388)

-0.039

(-0.336, 0.257)

0.017

(0.536, 0.501)

-0.117

(-0.256, 0.022)

Volume 3th tercile

-0.003

(-0.109, 0.103)

0.023

(-0.190, 0.235)

0.118

(-0.273, 0.509)

-0.410*

(-0.637, -0.182)

-0.405*

(-0.785, -0.025)

-0.158

(-0.329, 0.012)

API***

-0.004

(-0.007, 0.002)

0.008

(-0.011, 0.026)

-0.012

(-0.027, -0.004)

-0.006

(-0.018, 0.006)

0.007

(-0.013, 0.027)

0.001

(0.002, 0.004)

Innovator

0.662**

(0.451, 0.873)

0.571**

(0.411, 0.730)

0.148*

(0.051, 0.245)

-0.714**

(-0.989, -0.438)

-0.793

(-1.789, 0.204)

0.274**

(-0.138, 0.410)

CHAI++

-0.143*

(-0.274, -0.012)

-0.499

(-1.099, 0.102)

-0.550*

(-0.982, -0.117)

-0.279*

(-0.499, 0.060)

-0.666**

(-1.098, -0.235)

-0.193

(-0.582, 0.197)

PEPFAR+++

0.054

(-0.049, 0.157)

0.046

(-0.265, 0.358)

0.347

(0.092, 0.785)

0.486*

(0.091, 0.880)

-0.118*

(-0.233, 0.002)

0.084

(-0.040, 0.209)

R-square

0.578

0.455

0.481

0.269

0.221

0.408

Observations

793

492

397

484

309

489

  1. Linear regression models whether the dependent variable is the logarithm of price. The reference categories are: HIV Prevalence <2%; Low income countries; Volume 1st tercile
  2. * significant at 5%; ** significant at 1%; Robust 95% confidence intervals in parentheses; ***API = AIDS Program Index; +Abbreviation of the ARV drugs: ABC = abacavir; ddl = didanosine; LPV/r = lopinavir/ritonavir; RTV = ritonavir; TDV = tenofovir; ++CHAI = Clinton Foundation HIV/AIDS initiative; +++PEPFAR = President's Emergency Plan for AIDS Relief
  3. Data source: Global Price Reporting Mechanism 2005 to 2008
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