Characteristic
|
Slight
|
Moderate
|
Severe
|
P*
|
---|
Number of subjects
|
67
|
64
|
39
| |
Age (years)
|
61.0 (2.1)
|
61.6 (2.3)
|
62.7 (2.5)
|
0.002
|
Height (cm)
|
165.9 (5.7)
|
165.2 (6.5)
|
163.4 (4.9)
|
0.11
|
Weight (kg)
|
68.0 (9.9)
|
65.6 (9.7)
|
64.2 (7.9)
|
0.10
|
Body mass index
|
24.7 (3.1)
|
23.9 (3.0)
|
23.9 (2.5)
|
0.33
|
Systolic blood pressure (mmHg)
|
146.2 (16.9)
|
146.9 (21.6)
|
144.6 (22.2)
|
0.86
|
Diastolic blood pressure (mmHg)
|
84.3 (10.1)
|
83.5 (10.0)
|
84.4 (12.2)
|
0.88
|
Serum total cholesterol (mg/dL)
|
208.3 (34.7)
|
203.9 (32.9)
|
208.2 (30.5)
|
0.72
|
HDL cholesterol (mg/dL)
|
57.8 (15.0)
|
59.5 (16.1)
|
59.3 (14.2)
|
0.79
|
HbA1c (%)
|
5.30 (0.71)
|
5.27 (0.73)
|
5.33 (0.96)
|
0.93
|
Estradiol (E2) (pg/mL)
|
25.7 (6.4)
|
25.4 (6.1)
|
25.9 (6.4)
|
0.92
|
Testosterone (pg/mL)
|
13.2 (4.5)
|
12.7 (3.7)
|
13.2 (3.9)
|
0.76
|
Smoking habit
| | | | |
Never
|
13
|
17
|
13
|
0.47
|
Past
|
36
|
35
|
17
| |
Current
|
18
|
12
|
9
| |
Alcohol use
| | | | |
Never
|
3
|
7
|
3
|
0.66
|
Light
|
9
|
7
|
4
| |
Moderate
|
19
|
13
|
13
| |
Severe
|
36
|
37
|
19
| |
Medical history
| | | | |
Hypertension
|
27
|
27
|
14
|
0.67
|
Diabetes
|
11
|
9
|
5
|
0.96
|
CVD
|
3
|
5
|
2
|
0.70
|
CHD
|
6
|
10
|
8
|
0.36
|
Hepatic
|
14
|
15
|
10
|
0.83
|
Respiratory
|
7
|
7
|
1
|
0.41
|
Gastric
|
28
|
31
|
20
|
0.57
|
Hypercholesterolemia
|
15
|
8
|
3
|
0.098
|
- Values indicate number or mean (SD).
- CVD: cardiovascular disease; CHD: coronary heart disease.
- *Differences between groups were assessed using a chi-square test for categorical variables and an ANOVA for continuous variables.