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Table 2 Analytical studies investigating the relation between long-term PM exposure and cardiovascular and respiratory mortality.

From: Long-term particulate matter exposure and mortality: a review of European epidemiological studies

Reference, Study design, Country

Sex, age at enrolment

Number of deaths by cause

Risk indicator, measurement unit

Relative risk

(95% CI)

Hoek et al., 2002, NLCS cohort, the Netherlands

MF, 55-69

185

cardio-pulmonary

- Model 1a

- Model 1a

   

BS, 10 μg/m3

1.34 (0.68-2.64)

   

Living near a major road

1.95 (1.09-3.51)

   

- Model 2b

- Model 2b

   

BS, 10 μg/m3

1.71 (1.10-2.67)

Beelen et al., 2007, NLCS cohort, the Netherlands

MF, 55-69

7325 cardio-pulmonary

- Model 3c

- Model 3c

   

BS, 10 μg/m3

1.06 (0.98-1.15)

  

1046 respiratory

BS, 10 μg/m3

1.22 (0.99-1.49)

Filleul et al., 2005, PAARC cohort, France

MF, 25-59

546

cardio-pulmonary

TSP, 10 μg/m3 (24 areas)

1.01 (0.99-1.03)

   

TSP, 10 μg/m3 (18 areas)d

1.06 (1.01-1.12)

   

BS, 10 μg/m3 (24 areas)

1.00 (0.97-1.02)

   

BS, 10 μg/m3 (18 areas)d

1.05 (0.98-1.12)

Gehring et al., 2006, cohort, Germany

F, 50-59

139

cardio-pulmonary

Average 1-year concentration

PM10, 7 μg/m3

1.34 (1.06-1.71)

   

Average 5-year concentration

PM10, 7 μg/m3

1.59 (1.23-2.04)

Rosenlund et al., 2006, case-control, Sweden

MF, 45-70

272

myocardial infarction

All MI deaths

PM10, 5 μg/m3

1.39 (0.94-2.07)

   

In-hospital MI deaths

PM10, 5 μg/m3

1.21 (0.75-1.94)

   

Out of hospital MI deaths

PM10, 5 μg/m3

1.84 (1.00-3.40)

Naess et al., 2007a, cohort, Norway

 

Cardio-vascular

  
 

M, 51-70

2007

PM2.5, quartile increase

1.10 (1.05-1.16)

 

F, 51-70

946

PM2.5, quartile increase

1.14 (1.06-1.21)

 

M, 71-90

4531

PM2.5, quartile increase

1.05 (1.01-1.08)

 

F, 71-90

7480

PM2.5, quartile increase

1.03 (1.00-1.05)

  

COPD

  
 

M, 51-70

233

PM2.5, quartile increase

1.27 (1.11-1.47)

 

F, 51-70

203

PM2.5, quartile increase

1.09 (0.94-1.25)

 

M, 71-90

503

PM2.5, quartile increase

1.10 (1.00-1.21)

 

F, 71-90

516

PM2.5, quartile increase

1.05 (0.96-1.16)

  1. BS: black smoke; CI: confidence interval; COPD: chronic obstructive pulmonary disease; MI: myocardial infarction; NLCS: Netherlands Cohort Study; PAARC: Pollution Atmosphérique et Affections Respiratoires Chroniques; PM: particulate matter; TSP: total suspended particulate
  2. a Model 1: Local and regional effects were separately included in the model
  3. b Model 2: Local and regional effects were combined in a single variable
  4. c Model 3: Exposure was calculated according to local, urban and regional components
  5. d Six areas for which the NO/NO2 ratio was >3 were excluded