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Table 3 Plasma cotinine and expired carbon monoxide (CO) levels

From: Smoking cessation or reduction with nicotine replacement therapy: a placebo-controlled double blind trial with nicotine gum and inhaler

 

Cotinine

(ng/ml)

CO (ppm)

Outcome group

4 months (baseline)

p

12 months (baseline)

p

4 months (baseline)

p

12 months (baseline)

p

Abstainers*

80 (220) N = 46

<.001

40 (232) N = 45

<.001

4.5 (23.0) N = 51

<.001

2.7 (22.4) N = 48

<.001

Reducers*

184 (279) N = 63

<.001

216 (253) N = 50

NS

13.1 (26.4) N = 66

<.001

11.7 (26.3) N = 55

<.001

Failures

265 (259) N = 73

NS

271 (257) N = 80

NS

20.7 (19.4) N = 88

NS

17.2 (20.4) N = 90

<.001

  1. *Includes all subjects who were classed as Abstainers and Reducers in both the Active and Placebo treatment groups.