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Table 1 Characteristics of the Study Population

From: Factors associated with mortality in HIV-infected and uninfected patients with pulmonary tuberculosis

 

Mortality

 

Yes (n = 155)

No (n = 732)

Characteristics

Mean (SD) or % (Number)

Mean (SD) or % (Number)

Social and demographic variables

  

Age, yrs

35.97 (8.49)

31.35 (8.84)

Females

40.00% (62)

32.10% (235)

Karnofsky Score

71.74 (9.54)

75.17 (8.41)

Shillings* spent on food/person/day (quartiles)

   ≤ 250

28.37% (40)

23.14% (149)

   251-499

26.24% (37)

26.40% (170)

   500-750

26.24% (37)

27.17% (175)

   >750

19.15% (27)

23.29% (150)

TB related

  

AFB Smear Result positive at baseline

96.75% (149)

94.12% (688)

AFB Culture positive at baseline

66.67% (44)

68.82% (287)

Laboratory Results

  

Baseline Hemoglobin, g/dL

9.59 (1.59)

10.59 (1.82)

HIV- or Immune function related

  

HIV infected

90.32% (140)

45.22% (331)

Baseline WHO HIV stage

  

   3

85.96% (98)

93.48% (215)

   4

14.04% (16)

6.52% (15)

Baseline CD4 cell count/μL

238.15 (302.25)

564.04 (288.86)

Baseline CD3 cell count/μL

1086.23 (605.21)

1232.42 (501.09)

Baseline CD8 cell count/μL

785.61 (454.56)

601.85 (383.09)

CD4/CD8 Ratio

0.39 (0.71)

1.30 (0.90)

Log(10) viral load

5.11 (0.66)

4.38 (0.99)

   Q1

6.45% (10)

11.61% (85)

   Q2

14.19% (22)

9.97% (73)

   Q3

18.06% (28)

9.15% (67)

   Q4

34.84% (54)

5.60% (41)

Clinical signs and symptoms

  

Diarrhea

9.45% (12)

10.12% (58)

Fatigue

71.65% (91)

66.32% (380)

Fever

55.12% (70)

64.22% (368)

Nausea/Vomiting

5.51% (7)

8.90% (51)

Skin Rash

20.47% (26)

8.90% (51)

Oral thrush

12.60% (16)

1.40% (8)

Weight loss

81.89% (104)

80.63% (462)

Extrapulmonary TB

1.57% (2)

2.44% (14)

Anthropometry

  

BMI at enrolment, kg/m2

19.31 (3.04)

19.10 (2.64)

MUAC at enrolment, cm

23.25 (2.85)

23.25 (2.61)

  1. * 1000 Tanzanian Shillings ≈ 1 US Dollar at the time of the trial