Figure 1
From: A cost-utility analysis of cervical cancer vaccination in preadolescent Canadian females
Cohort model structure. 12-disease state Markov process model with 12 month cycle, simulates natural history of HPV infection and cervical cancer. Transition rates vary by age, HPV type, screening, treatment, vaccination. Simple screening module. Detected: subjects with disease detected through screening have same pathways but different probabilities. CIN: Cervical Intraepithelial Neoplasia.