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Table 2 Environmental risk factors – occupational exposure, farming related exposure and pets (> 1980)

From: A case-control study of sporadic Creutzfeldt-Jakob disease in Switzerland: analysis of potential risk factors with regard to an increased CJD incidence in the years 2001–2004

    

comparison with all control subjects

risk factor

n

total

mean (SD) or %

crude estimate

age and sex adjusted estimate

age, sex and education adjusted estimate

  

cases n = 69

controls n = 224

OR (95% CI)

p

OR (95% CI)

p

OR (95% CI)

p

medical profession

290

6.0

6.3

0.95 (0.30–2.98)

0.927

1.21 (0.36–4.09)

0.764

1.49 (0.43–5.15)

0.533

animal laboratory

290

4.5

0.9

5.18 (0.82–31.65)

0.075

5.32 (0.86–33.00)

0.073

9.55 (1.41–64.49)

0.021

pharmaceutical laboratory

290

1.5

0.5

3.36 (0.21–54.51)

0.393

3.45 (0.21–56.29)

0.385

3.39 (0.21–55.20)

0.390

research laboratory

290

1.5

2.2

0.66 (0.08–5.75)

0.707

0.62 (0.07–5.40)

0.662

0.68 (0.08–5.99)

0.730

work with animals (animal care, veterinarian)

290

14.9

8.1

2.00 (0.87–4.57)

0.101

2.06 (0.89–4.80)

0.092

1.45 (0.59–3.55)

0.419

work in meat industry

290

3.0

3.6

0.83 (0.17–4.00)

0.813

0.83 (0.17–4.05)

0.816

0.67 (0.13–3.33)

0.622

work in catering industry

290

6.0

2.2

2.77 (0.72–10.61)

0.138

3.07 (0.78–12.05)

0.108

2.81 (0.70–11.27)

0.144

work with animal products (e.g. leather)

290

4.5

3.1

1.44 (0.36–5.75)

0.600

1.43 (0.36–5.74)

0.616

1.45 (0.35–5.96)

0.610

farm work or stay (for > 1 week)

289

10.6

14.4

0.71 (0.30–1.69)

0.436

0.70 (0.29–1.68)

0.431

0.62 (0.25–1.50)

0.287

work with hoof or horn

288

15.4

13.0

1.22 (0.56–2.65)

0.622

1.23 (0.56–2.69)

0.604

1.12 (0.49–2.53)

0.794

work with bonemeal

287

6.3

8.5

0.72 (0.23–2.18)

0.557

0.67 (0.22–2.06)

0.484

0.75 (0.24–2.33)

0.617

work with dried blood

289

3.0

3.6

0.84 (0.17–4.05)

0.828

0.79 (0.16–3.85)

0.770

0.75 (0.15–3.83)

0.733

work with fertiliser

289

24.2

22.0

1.14 (0.60–2.17)

0.698

1.15 (0.60–2.20)

0.677

1.14 (0.59–2.22)

0.692

pet cat

289

31.8

46.2

0.54 (0.30–0.97)

0.040

0.55 (0.31–0.99)

0.046

0.57 (0.32–1.04)

0.067

pet dog

289

39.4

30.5

1.48 (0.84–2.62)

0.177

1.48 (0.84–2.62)

0.179

1.52 (0.85–2.72)

0.161

pet rodent

288

16.9

36.8

0.35 (0.17–0.71)

0.003

0.32 (0.16–0.66)

0.002

0.32 (0.16–0.66)

0.002