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Table 2 Environmental risk factors – occupational exposure, farming related exposure and pets (> 1980)

From: A case-control study of sporadic Creutzfeldt-Jakob disease in Switzerland: analysis of potential risk factors with regard to an increased CJD incidence in the years 2001–2004

     comparison with all control subjects
risk factor n
total
mean (SD) or % crude estimate age and sex adjusted estimate age, sex and education adjusted estimate
   cases n = 69 controls n = 224 OR (95% CI) p OR (95% CI) p OR (95% CI) p
medical profession 290 6.0 6.3 0.95 (0.30–2.98) 0.927 1.21 (0.36–4.09) 0.764 1.49 (0.43–5.15) 0.533
animal laboratory 290 4.5 0.9 5.18 (0.82–31.65) 0.075 5.32 (0.86–33.00) 0.073 9.55 (1.41–64.49) 0.021
pharmaceutical laboratory 290 1.5 0.5 3.36 (0.21–54.51) 0.393 3.45 (0.21–56.29) 0.385 3.39 (0.21–55.20) 0.390
research laboratory 290 1.5 2.2 0.66 (0.08–5.75) 0.707 0.62 (0.07–5.40) 0.662 0.68 (0.08–5.99) 0.730
work with animals (animal care, veterinarian) 290 14.9 8.1 2.00 (0.87–4.57) 0.101 2.06 (0.89–4.80) 0.092 1.45 (0.59–3.55) 0.419
work in meat industry 290 3.0 3.6 0.83 (0.17–4.00) 0.813 0.83 (0.17–4.05) 0.816 0.67 (0.13–3.33) 0.622
work in catering industry 290 6.0 2.2 2.77 (0.72–10.61) 0.138 3.07 (0.78–12.05) 0.108 2.81 (0.70–11.27) 0.144
work with animal products (e.g. leather) 290 4.5 3.1 1.44 (0.36–5.75) 0.600 1.43 (0.36–5.74) 0.616 1.45 (0.35–5.96) 0.610
farm work or stay (for > 1 week) 289 10.6 14.4 0.71 (0.30–1.69) 0.436 0.70 (0.29–1.68) 0.431 0.62 (0.25–1.50) 0.287
work with hoof or horn 288 15.4 13.0 1.22 (0.56–2.65) 0.622 1.23 (0.56–2.69) 0.604 1.12 (0.49–2.53) 0.794
work with bonemeal 287 6.3 8.5 0.72 (0.23–2.18) 0.557 0.67 (0.22–2.06) 0.484 0.75 (0.24–2.33) 0.617
work with dried blood 289 3.0 3.6 0.84 (0.17–4.05) 0.828 0.79 (0.16–3.85) 0.770 0.75 (0.15–3.83) 0.733
work with fertiliser 289 24.2 22.0 1.14 (0.60–2.17) 0.698 1.15 (0.60–2.20) 0.677 1.14 (0.59–2.22) 0.692
pet cat 289 31.8 46.2 0.54 (0.30–0.97) 0.040 0.55 (0.31–0.99) 0.046 0.57 (0.32–1.04) 0.067
pet dog 289 39.4 30.5 1.48 (0.84–2.62) 0.177 1.48 (0.84–2.62) 0.179 1.52 (0.85–2.72) 0.161
pet rodent 288 16.9 36.8 0.35 (0.17–0.71) 0.003 0.32 (0.16–0.66) 0.002 0.32 (0.16–0.66) 0.002