Table 1 Sociodemographic factors
comparison with all control subjects | |||||||||
|---|---|---|---|---|---|---|---|---|---|
risk factor | n total | mean (SD) or % | crude estimate | age and sex adjusted estimate | age, sex and education adjusted estimate | ||||
cases n = 69 | controls n = 224 | OR (95% CI) | p | OR (95% CI) | p | OR (95% CI) | p | ||
age (years) | 293 | 68.7 (9.6) | 69.6 (8.2) | 0.99 (0.96–1.02) | 0.449 | 0.99 (0.96–1.02)1 | 0.444 | 0.99 (0.96–1.02) | 0.450 |
age-group 41 – 59 years | 35 | 15.9 | 10.7 | 15 | 15 | 15 | |||
age-group 60 – 69 years | 103 | 33.3 | 35.7 | 0.63 (0.27–1.47) | 0.283 | 0.63 (0.27–1.47) | 0.281 | 0.61 (0.25–1.50) | 0.282 |
age-group 70 – 79 years | 112 | 36.2 | 38.8 | 0.63 (0.27–1.45) | 0.277 | 0.61 (0.26–1.42) | 0.249 | 0.61 (0.25–1.49) | 0.278 |
age-group 80 – 85 years | 43 | 14.5 | 14.7 | 0.66 (0.24–1.81) | 0.420 | 0.68 (0.25–1.86) | 0.452 | 0.65 (0.23–1.87) | 0.427 |
sex (male) | 293 | 65.2 | 57.1 | 1.41 (0.81–2.47) | 0.234 | 1.41 (0.80–2.47)1 | 0.232 | 1.70 (0.93–3.08) | 0.080 |
education: ≥ 10 school years | 289 | 44.6 | 71.4 | 0.32 (0.18–0.57) | 0.000 | 0.29 (0.16–0.52) | 0.000 | 0.29 (0.16–0.52) | 0.000 |
education: N° of school years | 289 | 11.0 (3.6) | 12.1 (3.2) | 0.90 (0.82–0.98) | 0.021 | 0.88 (0.80–0.97) | 0.009 | 0.88 (0.80–0.97) | 0.009 |
education: ≤ 9 school years grouped | 100 | 55.4 | 28.6 | 15 | 15 | 15 | |||
education: 10–12 school years grouped | 79 | 18.5 | 29.9 | 0.32 (0.15–0.67) | 0.002 | 0.31 (0.15–0.66) | 0.002 | 0.31 (0.15–0.66) | 0.002 |
education: ≥ 13 school years grouped | 100 | 26.2 | 41.5 | 0.32 (0.17–0.63) | 0.001 | 0.31 (0.16–0.61) | 0.001 | 0.28 (0.14–0.55) | 0.000 |
marital status (married) | 293 | 79.7 | 72.8 | 1.47 (0.76–2.83) | 0.250 | 1.32 (0.67–2.61) | 0.425 | 1.32 (0.65–2.67) | 0.445 |
having a partner | 293 | 79.7 | 73.7 | 1.40 (0.73–2.71) | 0.311 | 1.25 (0.63–2.28) | 0.527 | 1.24 (0.61–2.53) | 0.551 |
residence in German speaking cantons (vs. French & Italian speaking) | 293 | 76.8 | 75.9 | 1.05 (0.56–1.99) | 0.876 | 1.08 (0.56–2.07) | 0.822 | 1.03 (0.52–2.02) | 0.931 |
country of birth (foreign2) | 292 | 13.2 | 19.2 | 0.64 (0.30–1.40) | 0.263 | 0.64 (0.29–1.38) | 0.254 | 0.69 (0.31–1.52) | 0.355 |
having lived abroad2 (> 1980) | 289 | 6.1 | 4.0 | 1.53 (0.46–5.15) | 0.489 | 1.46 (0.42–5.04) | 0.549 | 1.60 (0.46–5.74) | 0.471 |
frequent travels abroad (= once per year, > 1980)4 | 119 | 83.3 | 35.4 | 9.13 (3.80–21.97) | 0.000 | 8.61 (3.47–21.34) | 0.000 | 9.31 (3.63–23.91) | 0.000 |
travel history to the U.K. (> 1980) | 276 | 7.6 | 22.4 | 0.28 (0.10–0.82) | 0.020 | 0.27 (0.09–0.79) | 0.017 | 0.29 (0.10–0.86) | 0.026 |
travel history to tropical countries (> 1980) | 276 | 15.1 | 28.3 | 0.45 (0.20–1.01) | 0.053 | 0.44 (0.19–0.99) | 0.046 | 0.43 (0.19–1.00) | 0.045 |
left-handed3 (vs. right) | 290 | 9.1 | 10.7 | 0.83 (0.33–2.13) | 0.704 | 0.83 (0.32–2.14) | 0.701 | 0.76 (0.29–1.98) | 0.577 |
dementia in family history | 291 | 19.4 | 15.6 | 0.77 (0.38–1.56) | 0.466 | 0.78 (0.38–1.59) | 0.494 | 0.64 (0.30–1.37) | 0.252 |