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Table 2 Measures used at baseline, one-and five-years in the ADDITION-Cambridge

From: The ADDITION-Cambridge trial protocol: a cluster – randomised controlled trial of screening for type 2 diabetes and intensive treatment for screen-detected patients

Measures Baseline 1-year 5-year
  C RC IT C RC IT C RC IT
Diabetes risk score calculation X X X       
Questionnaires measures          
1. Ethnic group, occupation, educational level and social class   X X       
2 Smoking status, alcohol consumption   X X   X X X X X
3. Rose angina questionnaire [51]   X X     X   
4. Self-reported history of angina, heart attack and stroke   X X   X X X X X
5. Medication adherence:          
   All drugs during the last month [40]   X X   X X   X X
   Hypoglycaemic drugs during the last month [40]      X X   X X
6. EuroQoL EQ-5D [47] & SF-36 [45]/SF-8 [46]   X X   X X X X X
7. Diabetes related quality of life: ADDQoL [44], Diabetes well-being: W-BQ 28 [44], Diabetes treatment satisfaction: DTSQ[44]      X X   X X
8. Spiegelberger Short form State Anxiety inventory [49]   X X   X X    
9. Consultation and relational empathy measure: CARE [48]   X X   X X    
10. Diabetes knowledge †      X X    
11. EPAQ-2 [41]   X X   X X   X X
12. IPAQ [42]   X X   X X X X X
13. EPIC food frequency questionnaire [43]   X X   X X   X X
14. Brief dietary questionnaire (adapted from the EPIC food frequency questionnaire) †        X X X
15. Costs comprising:          
   Personal patient costs †   X X       
   Health Service and medication use previous 3 months (adapted from the Aberdeen Health Service Research Unit questionnaire) †      X X X X X
16. Neuropathy questionnaire (adapted from the Michigan Screening Instrument) †   X X   X X   X X
Biological measures          
17. Waist circumference, height, weight, blood pressure, body fat impedance and ECG   X X   X X   X X
18. Fasting capillary blood glucose   X X       
19. Fasting, 30 and 120 min: venous whole blood glucose (OGTT), plasma glucose, plasma insulin.   X X       
20. HbA1c, total cholesterol, HDL and LDL cholesterol, triglyceride, Vitamin C, Urinalysis, Urine albumin/creatinine ratio, Urea and Electrolytes, Creatinine, Albumin, Biliribin, Alanine Amino Transferanse (ALT), Alkaline Phosphatase, Aspartate Amino Transferase (AST), Thyroid Stimulating Hormone (TSH)   X X   X X   X X
21. Modelled CVD risk calculated with the UKPDS risk engine [39]   X X   X X   X X
22. Stereoscopic fundal photography         X X
23. Mortality        X X X
  1. †: Questionnaire developed for the study