Quartile 1 < 0.18 μg/g | Quartile 2 0.18–0.33 μg/g | Quartile 3 0.34–0.62 μg/g | Quartile 4 ≥ 0.63 μg/g | p-trend | |
---|---|---|---|---|---|
Total testosterone, ng/mL | |||||
Never smokers | 5.03 (4.68, 5.41) | 4.88 (4.27, 5.58) | 4.12 (3.26, 5.22) | 4.24 (3.24, 5.55) | 0.06 |
Former smokers | 4.34 (3.91, 4.81) | 4.16 (3.60, 4.80) | 4.52 (4.20, 4.87) | 4.49 (4.05, 4.98) | 0.49 |
Current smokers | 5.74 (5.08, 6.48) | 5.78 (5.34, 6.27) | 6.09 (5.81, 6.39) | 6.39 (5.86, 6.96) | 0.12 |
Total estradiol, pg/mL | |||||
Never smokers | 31.7 (29.0, 34.6) | 34.0 (31.4, 36.7) | 34.3 (30.8, 38.2) | 30.2 (23.6, 38.7) | 0.97 |
Former smokers | 33.0 (30.1, 36.2) | 33.0 (31.0, 35.0) | 32.6 (30.8, 34.4) | 33.5 (31.0, 36.2) | 0.73 |
Current smokers | 40.2 (36.3, 44.5) | 39.1 (37.0, 41.3) | 44.3 (42.3, 46.5) | 43.2 (40.7, 45.8) | 0.26 |
SHBG, nmol/L | |||||
Never smokers | 32.4 (29.6, 35.3) | 32.6 (29.8, 35.6) | 31.3 (27.1, 36.1) | 32.5 (26.8, 39.3) | 0.88 |
Former smokers | 36.2 (30.6, 42.8) | 32.2 (29.7, 34.8) | 37.3 (33.5, 41.7) | 37.8 (34.1, 41.8) | 0.28 |
Current smokers | 39.3 (34.7, 44.5) | 36.3 (31.7, 41.6) | 33.7 (31.0, 36.6) | 37.6 (33.2, 42.7) | 0.71 |
Androstanediol glucuronide, ng/mL | |||||
Never smokers | 12.9 (12.0, 13.8) | 11.3 (9.9, 13.0) | 11.7 (9.7, 14.0) | 13.1 (11.0, 15.7) | 0.80 |
Former smokers | 14.0 (11.8, 16.7) | 11.8 (10.3, 13.6) | 10.5 (9.7, 11.3) | 11.7 (9.6, 14.4) | 0.64 |
Current smokers | 12.1 (9.8, 14.9) | 12.5 (10.0, 15.4) | 10.8 (8.7, 13.3) | 11.0 (9.3, 12.9) | 0.53 |
Estimated free testosterone, ng/mL | |||||
Never smokers | 0.102 (0.094, 0.111) | 0.099 (0.088, 0.111) | 0.084 (0.063, 0.112) | 0.085 (0.064, 0.114) | 0.14 |
Former smokers | 0.083 (0.075, 0.091) | 0.084 (0.071, 0.099) | 0.086 (0.079, 0.093) | 0.084 (0.076, 0.093) | 0.97 |
Current smokers | 0.109 (0.097, 0.123) | 0.114 (0.106, 0.123) | 0.129 (0.121, 0.137) | 0.126 (0.117, 0.136) | 0.09 |
Estimated free estradiol, pg/mL | |||||
Never smokers | 0.81 (0.73, 0.90) | 0.86 (0.79, 0.94) | 0.89 (0.78, 1.00) | 0.77 (0.60, 1.00) | 0.92 |
Former smokers | 0.84 (0.75, 0.94) | 0.86 (0.80, 0.92) | 0.82 (0.78, 0.87) | 0.84 (0.77, 0.91) | 0.87 |
Current smokers | 1.00 (0.90, 1.10) | 0.99 (0.92, 1.05) | 1.16 (1.09, 1.23) | 1.09 (1.01, 1.17) | 0.39 |
Estradiol*1000/total testosterone | |||||
Never smokers | 6.67 (6.06, 7.35) | 7.37 (6.08, 8.93) | 8.81 (6.75, 11.50) | 7.54 (6.20, 9.17) | 0.16 |
Former smokers | 8.08 (6.96, 9.37) | 8.41 (7.36, 9.60) | 7.62 (7.02, 8.28) | 7.89 (7.10, 8.77) | 0.71 |
Current smokers | 7.41 (6.75, 8.14) | 7.15 (6.62, 7.72) | 7.71 (7.25, 8.19) | 7.16 (6.58, 7.79) | 0.51 |
Total testosterone/SHBG | |||||
Never smokers | 0.539 (0.490, 0.593) | 0.520 (0.470, 0.575) | 0.457 (0.337, 0.619) | 0.453 (0.332, 0.619) | 0.25 |
Former smokers | 0.416 (0.364, 0.474) | 0.448 (0.382, 0.525) | 0.420 (0.380, 0.464) | 0.412 (0.370, 0.459) | 0.59 |
Current smokers | 0.507 (0.456, 0.563) | 0.552 (0.491, 0.621) | 0.628 (0.575, 0.685) | 0.588 (0.535, 0.646) | 0.31 |
Estradiol*1000/SHBG | |||||
Never smokers | 3.60 (3.09, 4.19) | 3.83 (3.37, 4.36) | 4.03 (3.29, 4.93) | 3.42 (2.62, 4.45) | 0.88 |
Former smokers | 3.35 (2.70, 4.15) | 3.77 (3.37, 4.20) | 3.20 (2.90, 3.53) | 3.25 (2.86, 3.70) | 0.52 |
Current smokers | 3.75 (3.30, 4.27) | 3.95 (3.44, 4.53) | 4.84 (4.35, 5.38) | 4.22 (3.66, 4.86) | 0.72 |