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Table 2 Comparison of estimated risk of hospitalization associated with influenza season using different methods of defining the influenza season.

From: Comparing estimates of influenza-associated hospitalization and death among adults with congestive heart failure based on how influenza season is defined

Flu Season Definition

Unadjusted Hazard Ratio (95% CI)

Adjusted Hazard Ratio* (95% CI)

Number of hospitalizations attributable to influenza

Rate of Attributable Excess hospitalizations** (95%CI)

5% Moving Average

1.09 (1.02–1.17)

1.10 (1.04–1.18)

109

12.72 (10.35 to 15.47)

10% Moving Average

1.04 (0.97–1.11)

1.09 (1.02–1.17)

74

8.64 (6.74 to 10.58)

First/Last Isolate

1.07 (0.995–1.14)

1.08 (1.01–1.16)

132

15.41 (12.54 to 18.74)

5% Total Season Isolates

1.07 (0.989–1.15)

1.08 (1.00–1.17)

51

5.95 (4.43 to 7.82)

  1. CI = confidence interval;
  2. * adjusted for trial, age group, NYHA class, co-morbidity index score, enalapril therapy, ejection fraction, and study site.
  3. **Rates are per 1,000 patient-years