Table 3 Cox multivariate regression for all cause, cardiovascular, ischaemic heart disease, cerebro disease and non-cardiovascular mortality. Effect of HbA1c level and diabetes status were modelled separately (models 1 and 2) and together (model 3)

All causes (n = 619)

Model 1

HbA_1c (per 1% increase)

1.1 (1.0,1.3)

0.03

1.1 (1.0, 1.2)

0.03

Model 2

Diabetes history (yes v no)

1.2 (0.8, 1.8)

0.38

1.2 (0.8, 1.9)

0.44

Model 3

HbA_1c (per 1% increase)

1.2 (1.0, 1.3)

0.04

1.2 (1.0, 1.4)

0.08

Diabetes history (yes v no)

0.9 (0.6, 1.4)

0.67

0.8 (0.4, 1.6)

0.61

Cardiovascular disease (n = 316)

Model 1

HbA_1c (per 1% increase)

1.2 (1.1, 1.4)

0.001

1.2 (1.1 1.4)

0.002

Model 2

Diabetes history (yes v no)

1.6 (1.0, 2.6)

0.056

1.5 (0.1, 2.6)

0.10

Model 3

HbA_1c (per 1% increase)

1.2 (1.1, 1.4)

0.01

1.2 (1.1, 1.5)

0.01

Diabetes history (yes v no)

1.1 (0.6, 1.8)

0.79

0.9 (0.5, 1.8)

0.81

Ischaemic heart disease (n = 165)

Model 1

HbA_1c (per 1% increase)

1.2 (1.1, 1.5)

0.01

1.2 (1.0, 1.4)

0.01

Model 2

Diabetes history (yes v no)

1.7 (1.0, 3.1)

0.08

1.5 (0.8, 3.0)

0.24

Model 3

HbA_1c (per 1% increase)

1.2 (1.0, 1.5)

0.06

1.3 (1.0, 1.6)

0.03

Diabetes history (yes v no)

1.2 (0.6, 2.1)

0.63

0.8 (0.4, 1.9)

0.68

Cerebro disease (n = 120)

Model 1

HbA_1c (per 1% increase)

1.2 (1.0, 1.5)

0.08

1.1 (0.9, 1.5)

0.29

Model 2

Diabetes history (yes v no)

1.6 (0.8, 3.3)

0.17

1.4 (0.7, 2.7)

0.40

Model 3

HbA_1c (per 1% increase)

1.2 (0.9, 1.5)

0.29

1.1 (0.8, 1.6)

0.42

Diabetes history (yes v no)

1.2 (0.6, 2.8)

0.61

1.0 (0.4, 2.4)

0.97

Non-cardiovascular disease (n = 303)

Model 1

HbA_1c (per 1% increase)

1.0 (0.9, 1.2)

0.87

1.0 (0.8, 1.2)

0.97

Model 2

Diabetes history (yes v no)

0.8 (0.5, 1.6)

0.58

0.8 (0.4, 1.7)

0.65

Model 3

HbA_1c (per 1% increase)

1.1 (0.9, 1.4)

0.57

1.1 (0.8, 1.4)

0.68

Diabetes history (yes v no)

0.8 (0.4, 1.6)

0.46

0.7 (0.2, 2.2)

0.58