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Table 3 Performance of sets of selective screening criteria for diabetes mellitus among participants in SUNSET

From: Prevalence of diabetes mellitus and the performance of a risk score among Hindustani Surinamese, African Surinamese and ethnic Dutch: a cross-sectional population-based study

  

Source

AUC (bCI) c

Sens (%, CI)

Spec (%, CI)

Screen (%)

Prev (%)

NNS

Set criteria for Hindustani Surinamese

1

age ≥ 45 years

DCGP

0.62

(0.58–0.67)

66.3

(55.2–75.9)

57.6

(51.2–63.8)

48.5

35.0

3

2

age ≥ 45 and BMI > 25 kg/m2

ADA

0.65

(0.61–0.71)

66.3

(55.2–75.9)

57.6

(51.2–63.8)

48.5

35.0

3

3

criteria 2, and have additional risk factors, as followsa

ADA extended

0.74

(0.70–0.79)

79.5

(69.0–87.3)

47.4

(41.0–53.8)

56.4

35.5

3

4

tailored risk scoreb

present study

0.74

(0.70–0.79)

75.9

(65,.0–84.3)

54.1

(47.6–60.4)

53.5

35.8

3

Set criteria for African Surinamese

1

age ≥ 45 years

DCGP

0.62

(0.58–0.67)

62.7

(50.7–73.3)

61.4

(57.0–65.6)

41.7

19.0

6

2

age ≥ 45 and BMI > 25 kg/m2

ADA

0.68

(0.65–0.75)

59.5

(47.4–70.5)

72.6

(68.5–76.3)

81.1

14.2

8

3

criteria 2, and have additional risk factors, as followsa

ADA extended

0.79

(0.76–0.85)

78.1

(66.6–86.6)

60.7

(56.3–65.0)

44.1

22.1

5

4

tailored risk scoreb

present study

0.80

(0.75–0.85)

79.2

(67.7–87.5)

62.3

(57.9–66.5)

42.8

23.0

5

Set criteria for ethnic Dutch

1

age ≥ 45 years

DCGP

0.57

(0.51–0.63)

78.8

(60.6–90.4)

35.6

(31.2–40.2)

65.4

8.2

13

2

age ≥ 45 and BMI > 25 kg/m2

ADA

0.72

(0.65–0.77)

72.7

(54.2–86.1)

72.7

(60.3–69.3)

79.8

8.0

13

3

criteria 2, and have additional risk factors, as followsa

ADA extended

0.79

(0.75–0.87)

71.9

(53.0–85.6)

71.2

(66.7–75.3)

31.7

15.0

7

4

tailored risk scoreb

present study

0.78

(0.73–0.85)

77.4

(58.5–89.7)

68.8

(64.2–73.1)

34.3

14.9

7

  1. a physically inactive or 1st-degree relative with DM or high risk ethnic group (Hindustani Surinamese, i.e. South Asian) or hypertensive or reduced HDL and/or elevated triglyceride or history of cardiovascular disease.
  2. b optimal screening criteria identified from multivariate analysis (ethnic groups, age, BMI, waist circumference, resting heart rate, first-degree relative with DM, hypertension, history of cardiovascular disease)
  3. c bCI: The 'Confidence interval' around the score was estimated via a bootstrapping procedure [20], the 2.5 and 97.5 percentiles are listed between brackets. The cut-off value for the SUNSET score was 0.200 for Hindustani Surinamese, 0.077 for African Surinamese and 0.055 for ethnic Dutch. DM = diabetes mellitus (fasting plasma glucose ≥ 7.0 mmol/l and/or self-reported), CI = 95%-confidence interval, DCPG = Dutch College of General Practitioners, ADA = American Diabetes Association, AUC = area under the curve, a measure of diagnostic accuracy, sens = sensitivity of the criteria (value closest to, but not over 80%), spec = specificity corresponding to the listed sensitivity, screen = percentage of the total population in this study that is screened, prev = prevalence in the screened population (the predictive value positive), NNS = number needed to screen to detect a case of DM in this study, BMI = body mass index