Table 1 Clinical and metabolic characteristics of the subjects as a function of the diagnosis of MS based on the NCEP-ATPIII criteria

Females

60.6(436)

51.4(262)

82.8(174)

< 0.001

Age;years

66.9(SD = 10.9)

63.2(SD = 11.2)

70.6(SD = 9.3)

< 0.001

Obesity

39.6(285)

22.3(114)

81.4(171)

< 0.001

BMI(kg/m²)

29.1(SD = 5.2)

27.7(SD = 4.6)

32.1(SD = 5.2)

< 0.001

   FEMALES

27.9(SD = 6.0)

27.5(SD = 5.4)

33.5(SD = 4.9)

< 0.001

   MALES

27.7(SD = 4.7)

27.1(SD = 3.9)

28.7(SD = 5.3)

< 0.001

Abdominal circumference(cm)

100.7(SD = 11.7)

95.8(SD = 13.0)

107.2(SD = 13.8)

< 0.03

Blood pressure

48.9(352)

36.1(184)

80.0(168)

< 0.001

BPS(mmHg)

132.0(SD = 17.6)

130.3(SD = 19.4)

142.0(SD = 18.7)

< 0.001

   FEMALES

131.6(SD = 20.7)

127.4(SD = 19.3)

140.4(SD = 17.8)

< 0.001

   MALES

133.4(SD = 18.1)

129.1(SD = 16.3)

145.6(SD = 18.7)

< 0.001

BPD(mmHg)

78.1(SD = 11.6)

78.4(SD = 11.7)

82.4(SD = 11.1)

< 0.001

   FEMALES

78.5(SD = 11.7)

76.4(SD = 11.1)

81.6(SD = 10.5)

< 0.001

   MALES

79.6(SD = 11.6)

79.0(SD = 11.0)

83.7(SD = 11.6)

< 0.001

Diabetes mellitus

19.7(142)

8.8(45)

60.5(127)

< 0.001

Baseline glycemia(mg/dL)

106.7(SD = 38.7)

102.1(SD = 31.7)

127.4(SD = 55.8)

< 0.001

   FEMALES

111.4(SD = 42.3)

97.3 (SD = 27.5)

139.4(SD = 51.8)

< 0.001

   MALES

114.8(SD = 46.0)

103.6(SD = 41.0)

133.5(SD = 48.1)

< 0.001

HbA_1c;%

5.6(SD = 1.5)

5.4(SD = 1.3)

6.2(SD = 2.0)

< 0.001

   FEMALES

6.04 (SD = 1.8)

5.32(SD = 1.2)

6.7(SD = 2.0)

< 0.001

   MALES

6.11(SD = 1.9)

6.03(SD = 2.1)

6.2(SD = 1.6)

< 0.001

Dyslipemia

29.0(209)

16.1(82)

60.5(127)

< 0.001

Total cholesterol(mg/dL)

219.2(SD = 40.1)

217.3(SD = 42.5)

226.6(SD = 46.3)

< 0.01

   FEMALES

219.6(SD = 41.5)

215.4(SD = 44.2)

239.7(SD = 52.6)

< 0.001

   MALES

218.5(SD = 43.9)

217.9(SD = 43.9)

223.5(SD = 42.8)

< 0.01

LDL-cholesterol(mg/dL)

141.3(SD = 36.3)

140.9(SD = 35.9)

143.2(SD = 36.7)

NS

   FEMALES

141.2(SD = 36.1)

139.8(SD = 36.3)

141.7(SD = 36.5)

NS

   MALES

145.2(SD = 37.2)

143.3(SD = 35.8)

147.2(SD = 39.4)

NS

HDL-cholesterol(mg/dL)

54.4(SD = 19.0)

54.0(SD = 16.6)

50.8(SD = 17.4)

< 0.001

   FEMALES

53.2(SD = 18.2)

58.7(SD = 18.4)

52.4(SD = 16.1)

< 0.001

   MALES

50.9(SD = 22.3)

52.2(SD = 20.6)

50.1(SD = 20.8)

NS

Triglycerides(mg/dL)

151.4(SD = 109.6)

147.0(SD = 107.0)

165.4(SD = 118.3)

< 0.001

   FEMALES

134.0(SD = 79.2)

104.4(SD = 59.2)

177.5(SD = 87.1)

< 0.001

   MALES

174.0(SD = 135.7)

148.0 (SD = 123)

210.5(SD = 146.2)

< 0.002

Microalbuminuria(mg/d)

38.3(SD = 131.2)

18.2(SD = 64.1)

103.8(SD = 233)

< 0.002

   FEMALES

17.8(SD = 42.3)

13.7(SD = 18.2)

24.5(SD = 64.1)

< 0.001

   MALES

65.5(SD = 191.3)

42.5(SD = 112.4)

101.7(SD = 269)

< 0.001

CVD risk(% at 10 years)

13.8(SD = 10.0)

13.4(SD = 8.3)

23.8(SD = 10.0)

< 0.001

   FEMALES

8.7(SD = 7.9)

6.5(SD = 5.3)

17.3(SD = 10.0)

< 0.001

   MALES

19.7(SD = 11.1)

14.4(SD = 9.8)

26.4(SD = 11.6)

< 0,001

REGICOR(% at 10 years)

8.8(SD = 9.8)

7.2(SD = 8.9)

10.7(SD = 9.5)

< 0.001

   FEMALES

3.7(SD = 5.3)

2.9(SD= 4.7)

5.6(SD = 7.1)

< 0.001

   MALES

10.1(SD = 8.8)

8.2(SD = 9.0)

13.5(SD = 9.4)

< 0.001

CVD complications

19.7(142) 113 individuals

11.0(56) 55 individuals

40.9(86) 58 individuals

< 0.001

Cerebrovascular

3.3(24)

2.3(12)

5.7(12)

< 0.001

Coronary

4.2(30)

2.9(15)

7.1(15)

< 0.001

Peripheral vascular

4.9(35)

3.3(17)

8.6(18)

< 0.001

Retinopathy

2.5(18)

1.4(7)

5.2(11)

< 0.02

Nephropathy

4.0(29)

0.8(4)

11.9(25)

< 0.001

Neuropathy

0.8(6)

0.2(1)

2.4(5)

< 0.001