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Table 2 Operationalised criteria for impairment in functioning (B1), and decline from a previous level of functioning (B2) when applied to the Cuban population based study data set, by clinical dementia status

From: The 10/66 Dementia Research Group's fully operationalised DSM-IV dementia computerized diagnostic algorithm, compared with the 10/66 dementia algorithm and a clinician diagnosis: a population validation study

  Prevalence (%) in those with clinically diagnosed dementia Prevalence (%) (high education controls) Prevalence (%) (low education controls)
B1 criterion requires that the cognitive deficits in Criteria A1 and A2 each cause significant impairment in social or occupational functioning
Memory impairment reported by informant, or 77 7 11
problems in two or more memory areas by informant report at least one of which must be 'frequent', or 90 26 32
any significant self-reported memory impairment (Q341, Q351, Q352 or Q361 >= 1) 69 65 66
Any of the above memory impairments, and 95 67 69
General impairment – one or more informant reported deficits (reduced activities, loss of hobby or skills, problems with household chores, change in ability to handle money, gets lost in the community or at home) 88 11 16
B2 criterion requires that the cognitive deficits described in A1 and A2 represent a significant decline from a previous level of functioning
B2_1 a 'change in activities', and/or 68 7 11
B2_2 a 'general decline in mental function' and/or 80 6 9
B2_3 an overall deterioration and/or 83 5 7
B2_4 gradual decline over two or more years, and 71 4 6
B2_5 the impairment is not considered to date from birth or early life 100 100 100