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Table 4 Prevalence of multiple prescription medication classes (upper decile by age) during follow-up by age group and ACE Score

From: Adverse childhood experiences and prescription drug use in a cohort study of adult HMO patients

 

Age 18–44 years

Age 45–64 years

Age 65–89 years

ACE Score

Top 10% (%)

OR* (95% CI)

Top 10% (%)

OR* (95% CI)

Top 10% (%)

OR* (95% CI)

   0

12.67

1.00 (referent)

10.14

1.00 (referent)

14.06

1.00 (referent)

   1

16.27

1.39 (1.06–1.82)

11.51

1.14 (0.93–1.41)

15.14

1.14 (0.94–1.39)

   2

17.54

1.53 (1.14–2.04)

12.08

1.21 (0.96–1.53)

14.56

1.11 (0.87–1.43)

   3

18.42

1.51 (1.09–2.09)

13.44

1.38 (1.05–1.80)

16.72

1.26 (0.90–1.76)

   4

18.48

1.47 (1.04–2.07)

16.38

1.65 (1.22–2.24)

22.42

1.83 (1.24–2.72)

   5 or more

25.27

2.11 (1.54–2.89)

21.52

2.22 (1.68–2.92)

19.23

1.56 (0.93–2.60)

Overall

16.97

 

12.31

 

14.98

 

p-value, trend

 

< 0.0001

 

< 0.0001

 

0.0020

  1. * Odds ratio (OR) and 95% confidence interval (CI) adjusted for age, sex, race, education