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Table 4 Major Birth Defects* among French PGWV's Children Born after the Mission (N = 5,183)

From: Reproductive health and pregnancy outcomes among French gulf war veterans

 

Children born in

All children

 

1991–1992

1993–2001

Total

Rate (p.10,000)

[95%CI]

Any major birth defect

21

119

140

270.1

[227.2–318.7]

Central nervous system

2

4

6

11.6

[4.2–25.2]

   Neural tube defects

1

2

3

5.8

[1.2–16.9]

   Hydrocephalus

0

1

1

1.9

[0.1–10.8]

   Other malformation of central nervous system

1

1

2

3.9

[0.5–13.9]

Eye, ear, face and neck

1

8

9

17.4

[7.9–33.0]

   Eye

1

3

4

7.7

[2.1–19.8]

   Ear

0

2

2

3.9

[0.5–13.9]

   Other malformation of eye, ear, face, nose

0

3

3

5.8

[1.2–16.9]

Circulatory system

2

13

15

28.9

[16.2–47.7]

   Congenital malformation of heart

0

12

12

23.2

[12.0–40.4]

   Other malformation of circulatory system

2

1

3

5.8

[1.2–16.9]

Respiratory system

1

2

3

5.8

[1.2–16.9]

Cleft lip/palate

0

3

3

5.8

[1.2–16.9]

Digestive system

3

10

13

25.1

[13.4–42.9]

   TOF and other malformations of large intest., rectum, anal canal

0

3

3

5.8

[1.2–16.9]

   Other malformation of digestive system

3

7

10

19.3

[9.3–35.5]

Genital system

2

8

10

19.3

[9.3–35.5]

Urinary system

2

16

18

34.7

[20.6–54.9]

   Renal anomalies

0

7

7

13.5

[5.4–27.8]

   Urinary tract anomalies

2

9

11

21.2

[10.6–38.0]

Musculoskeletal system

4

20

24

46.3

[29.7–68.9]

   Limb reduction

0

2

2

3.9

[0.5–13.9]

   Polydactyly and syndactyly

0

3

3

5.8

[1.2–16.9]

   Other limb malformation

1

11

12

23.2

[12.0–40.4]

   Anomalies of diaphragm, exomphalus, gastrochisis

0

3

3

5.8

[1.2–16.9]

   Other musculoskeletal anomalies

3

3

6

11.6

[4.2–25.2]

Other specific non-chromosomal syndromes

2

7

9

17.4

[7.9–33.0]

   Specified syndromes (non-chromosomal)

0

3

3

5.8

[1.2–16.9]

   Other non-chromosomal malformations

2

4

6

11.6

[4.2–25.2]

Chromosomal

2

12

14

27

[14.8–45.3]

   Down syndrome

2

4

6

11.6

[4.2–25.2]

   Other chromosomal

0

8

8

15.4

[6.7–30.4]

  1. * excluded: minor or unspecified anomalies of ear, undescended testes, unspecified congenital deformity of hip, unspecified congenital deformity of feet, naevus