Figure 4

Timecourse of eradication. Time course dynamics among a community where initial conditions are taken to be the equilibrium values of an existing infection, for a vaccine with 95% efficacy and 98% immunogenicity. A. If 65% of children are vaccinated, but no adult vaccination occurs, the prevalence in the sexually active cohort is reduced to approximately half of the previous disease burden after 150 years and remains so thereafter. B. If 65% of children and 40% of adults are vaccinated, the number of infections in the sexually active cohort continues to decline, eventually approaching zero. All other parameters as in Figure 4A.