Figure 1
The model. Schematic representation of the model representing flow of individuals from pre- to post-vaccination. School-aged girls may be vaccinated (C V ) or unvaccinated (C U ), depending on the proportion vaccinated (p) and the immunogenicity of the vaccine (ε). Children progress to sexually active adults at rate α. Unvaccinated adult women (A U ) can either be vaccinated (f) or become infected (I U ), with probability β N , when they meet an infected man N . Vaccinated adult women (A V ) can also become infected (I V ), but with reduced transmissibility, due to the efficacy of the vaccine ψ. Unvaccinated men (M) become infected upon contact with infected women, with transmission probability β M . The mortality rate of children is μ C and the leaving rate of adults is μ.