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Table 4 Serum folate and folic acid (μg/L). Samples collected on day 7 of regime A bread (50 μg in each slice) pre and post prandially.

From: Folic acid fortification and public health: Report on threshold doses above which unmetabolised folic acid appear in serum

  pre 50 μg 1 hour post 2 hrs post 3 hrs post 4 hrs post 1 hour post 2nd slice 2 hrs post 3 hrs post
Serum folate i ii iii iv v vi vii viii
Mean 16.91 16.30 16.99 16.88 17.40 15.56 15.40 14.82
SD 6.55 6.62 6.42 6.24 7.12 5.77 6.04 5.21
CI (95%) 13.75 – 20.06 13.11 – 19.49 13.89 – 20.08 13.87 – 19.88 13.97 – 20.83 12.78 – 18.34 12.49 – 18.31 12.31 – 17.33
  1. This table illustrates mean total serum folate (μg/L) concentrations in a group of healthy adult subject (n = 19) exposed to a folic fortified bread for 1-week. Subject were pre-saturated with folic acid supplements for 14-weeks prior to the bread. The bread was fortified with 50 μg folic acid per slice, which was administered twice a day for seven days. The samples shown here were collected on the 7th day of bread consumption pre-prandially and post-prandially. Standard deviations and confidence intervals are also shown. Serum folic acid was not detectable at any sampling points
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