Table 2 Changes in clinical outcome in baseline, three months and 12 months
n | Baseline mean (SD) | Change from baseline to 3 months* mean (95% CI) | Change from baseline to 12 months mean (95% CI) | Change at 12 months % | |
|---|---|---|---|---|---|
Weight (kg) | 237 | 91.7 (17.7) | -2.38 (-2.79,-1.98) | -2.52 (-3.19,-1.85) | -2.7 |
Body-mass index (kg/m2) | 237 | 33.5 (5.9) | -0.88 (-1.03,-0.74) | -0.93 (-1.17,-0.69) | -2.8 |
Waist circumference (cm) | 236 | 104.9 (13.0) | -3.16 (-3.72,-2.60) | -4.17 (-4.87,-3.48) | -4.0 |
Hip circumference (cm) | 236 | 115.7 (12.5) | -1.56 (-2.04,-1.07) | -2.65 (-3.26,-2.05) | -2.3 |
Plasma glucose (mmol/l) | |||||
Fasting | 237 | 5.53 (0.54) | 0.00 (-0.07,0.08) | -0.14 (-0.20,-0.07) | -2.5 |
2 Hr oral glucose challenge | 232 | 6.70 (1.69) | - | -0.58 (-0.79,-0.36) | -8.6 |
Serum lipids (mmol/l) | |||||
Total cholesterol | 237 | 5.67 (1.15) | -0.21 (-0.32,-0.09) | -0.29 (-0.40,-0.18) | -5.1 |
Low-density lipoprotein cholesterol | 229 | 3.44 (0.99) | -0.16 (-0.25,-0.07) | -0.25 (-0.34,-0.16) | -7.3 |
High-density lipoprotein cholesterol | 237 | 1.34 (0.37) | 0.01 (-0.02,0.03) | 0.06 (0.03,0.09) | +4.4 |
Triglycerides | 237 | 1.90 (1.00) | -0.10 (-0.20,0.01) | -0.15 (-0.24,-0.05) | -7.6 |
Blood pressure (mmHg) | |||||
Systolic | 236 | 132.1 (17.1) | -1.67 (-3.3,-0.04) | -1.01 (-2.60,0.58) | -0.8 |
Diastolic | 236 | 81.0 (9.9) | -0.99 (-2.18,0.20) | -2.14 (-3.33,-0.94) | -2.6 |