Table 1 The CHD mortality fall in Ireland attributable to risk factor changes in individuals with and without recognised coronary heart disease, including sensitivity analyses (minimum and maximum estimates)
Relative change in population risk factor level (%) | Deaths prevented or postponed * (minimum and maximum estimates) | |||
|---|---|---|---|---|
In healthy subjects (Primary prevention) | In CHD patients (Secondary Prevention) | TOTALS | ||
SMOKING Total Change | -14.2% | 275 (20–485) | 410 (310–800) | 685 (330 – 1,285) |
CHOLESTEROL Total change | -4.6% | 1,230 (1060–1,520) | 375 (170–770) | 1,605 (1,230 – 2,290) |
Fall Attributable to diet | 1,185 (1050–1,445) | 115(65–215) | 1,300 (1,115–1,660) | |
Fall Attributable to statins | 45(10–75) | 260 (105–555) | 305 (115–630) | |
BLOOD PRESSURE Total Change | -7.2% | 210 (115–365) | 30 (20–65) | 240 (135–430) |
Secular trends | 140(85–235) | 30(20–65) | 170 (105–300) | |
Hypertension therapy | 70(30–130) | ** | 70(30–130) | |
All 3 major risk factors | 1,715(68%) (1,195–2,370) | 815(32%) (500–1,635) | 2,530 (1,695–4,005) |