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Table 3 Distribution of cardiovascular risk categories and estimated costs associated with treatment of hypertension, dyslipidemia and diabetes mellitus

From: Prevalence of cardiovascular risk factors in a middle-income country and estimated cost of a treatment strategy

     

Cost

     

2004

2005

Condition/criterion

Associated conditions

Risk*

Medication

Prevalence in population aged 25–64 (%)

Cost per day per treated patient (SCR)

Annual cost for all cases aged ≥25 yrs (SCR million)

Per capita cost for total population per year (US$)

Cost per day per treated patient (SCR)

Annual cost for all cases aged ≥25 yrs (SCR million)

Per capita cost for total population per year (US$)

Diabetes (DM)

          

FBG ≥10 mmol/l

 

High

Metformin 1.5 g/d & Glibenclamide 10 mg/d

4.9

6.05

4.95

12.4

0.66

0.54

1.3

   

Addition of insulin 20 U (in 10% of cases)

 

3.40

0.28

0.7

7.72

0.63

1.6

FBG 7–9 mmol/l

 

High

Metformin 1.5 g/d

3.6

4.83

2.92

7.3

0.48

0.29

0.7

FBG <7 mmol/l

Treatment for DM

High

Metformin 1 g/d

0.9

3.19

0.45

1.1

0.32

0.05

0.1

Total diabetes

   

9.3

 

8.60

21.5

 

1.51

3.8

Hypertension

          

≥180/110 mmHg

-

High

2 drugs (20%), 3 drugs (70%), 4 drugs (10%)

3.1

4.10

2.11

5.3

1.47

0.76

1.9

160–179/100–109

≥3 MRF or DM

High

2 drugs (60%), 3 drugs (30%), 4 drugs (10%)

2.3

3.47

1.33

3.3

1.26

0.48

1.2

160–179/100–109

0–2 MRF, not DM

Medium

1 drug (10%), 2 drugs (60%), 3 drugs (30%)

5.6

2.78

2.63

6.6

1.01

0.96

2.4

140–159/90–99

≥3 MRF or DM

High

1 drug (20%), 2 drugs (70%), 3 drugs (10%)

5.6

2.27

2.14

5.4

0.83

0.79

2.0

140–159/90–99

1–2 MRF, not DM

Medium

1 drug (60%), 2 drugs (40%)

12.1

1.32

2.67

6.7

0.50

1.01

2.5

140–159/90–99

0 MRF

Low

-

4.3

0

  

0

  

<140/90

Treatment and ≥1 MRF

≥Medium

1 drug (70%), 2 drugs (30%)

6.9

1.12

1.28

3.2

0.43

0.49

1.2

Total hypertension

   

39.9

 

12.16

30.4

 

4.48

11.2

High cholesterol

          

≥8 mmol/l

 

High

Rosuvastatin 10 mg/d (80%), 20 mg (20%)

3.1

9.37

4.80

12.0

8.77

4.49

11.2

7–7.9 mmol/l

≥2 MRF or DM

High

Rosuvastatin 10 mg/d

3.5

7.81

4.56

11.4

7.31

4.27

10.7

6–6.9 mmol/l

≥3 MRF or DM

High

Rosuvastatin 10 mg/d

2.8

7.81

3.71

9.3

7.31

3.47

8.7

Total dyslipidemia

   

9.4

 

13.07

32.7

 

12.24

30.6

Any condition

   

42.7

 

33.8

84.6

 

18.22

45.6

  1. *CVD risk assessed based on following risk factors: age ≥55 for men; smoking; total cholesterol ≥6.2 mmol/l (240 mg/dl); HDL-cholesterol <1.0 mmol/l (40 mg/dl), BP ≥140/90 mmHg or treatment, obesity (body mass index ≥30 kg/m2); SCR: Seychelles rupees.