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Table 2 Adjusted Hazard Ratios of pregnancy and 95% confidence intervals according to male gonadal dose.

From: Male gonadal dose of ionizing radiation delivered during X-ray examinations and monthly probability of pregnancy: a population-based retrospective study

  n % HR * 95% CI p values
Male gonadal dose (mGy)       0.55
   No X-ray examination 491 48.0 1.03 0.80 1.31  
   0.01–0.20 321 31.4 1    p for trend
   0.21–2.00 101 9.9 0.86 0.59 1.26 0.27
   2.01–5.00 55 5.4 1.32 0.81 2.15  
   5.01–10.00 24 2.3 1.38 0.68 2.80  
   > 10.00 31 3.0 1.44 0.73 2.86  
Female age (years)       0.15
   < 20 21 2.1 0.57 0.28 1.17  
   20–24 321 31.4 1.00 0.79 1.28 p for trend
   25–29 466 45.5 1    0.05
   30–34 177 17.3 0.79 0.59 1.07  
   35–39 34 3.3 0.88 0.45 1.71  
   ≥40 4 0.4 0.19 0.04 1.00  
Menstrual cycle regularity       0.09
   Regular 708 69.2 1    
   Irregular 159 15.5 0.69 0.46 1.03  
   Oral contraception as usual birth control 156 15.3 1.23 0.86 1.78  
Menstrual cycle length (days)       0.07
   < 21 16 1.6 0.91 0.36 2.29  
   21–27 255 24.9 1.24 0.90 1.70  
   28 433 42.4 1    
   29–35 251 24.6 0.92 0.66 1.27  
   > 35 68 6.6 0.51 0.27 0.95  
Female tobacco consumption (cigarettes/day)       0.24
   0 639 62.5 1    
   1–10 244 23.8 0.92 0.71 1.20 p for trend
   11–20 129 12.6 0.86 0.61 1.20 0.08
   > 20 11 1.1 0.36 0.13 1.02  
Female genital and urinary tract diseases †,§       0.16
   No 939 91.8 1    
   Yes 84 8.2 0.75 0.50 1.12  
Male age (years)       0.42
   < 25 162 15.8 0.74 0.51 1.09  
   25–29 466 45.6 0.94 0.74 1.21 p for trend
   30–34 288 28.2 1    0.36
   35–39 87 8.5 0.81 0.53 1.24  
   ≥ 40 20 1.9 0.68 0.30 1.54  
Male genital and urinary tract diseases †,¶       0.80
   No 888 86.8 1    
   Yes 135 13.2 0.95 0.68 1.33  
  1. (n = 1023 pregnancies or periods of involuntary infertility lasting one year or more for 657 couples living in Beaumont-Hague and in the Saint-Brieuc area, France).
  2. * Hazard Ratio (HR) of pregnancy adjusted for calendar year at the beginning of the period of unprotected intercourse, area of inclusion and for the variables detailed in the table. A value below 1 indicates a decreased probability of pregnancy compared to the reference category.
  3. At the beginning of the period of unprotected intercourse.
  4. During the period of unprotected intercourse (time-dependent variable). Sample sizes are given for the first month of the period of unprotected intercourse.
  5. § Previous history of ovarian or uterine cancer, salpingitis, endometriosis, ovarian cysts or infection, genital tract operation, Chlamydia infection.
  6. Previous history of cancer, mumps with testes injury, cryptorchidism, inguinal hernia, varicocele, testes torsion, gonococci, epididymitis, cystis, prostates, genital tract operation, Chlamydia infection.