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Table 1 Demographic and biochemical characteristics of the patients in the database and univariate hazard ratio for first atherosclerotic event

From: Relative risk for cardiovascular atherosclerotic events after smoking cessation: 6–9 years excess risk in individuals with familial hypercholesterolemia

Risk factor

value

Univariate HR (95% CI)

Gender (% men)

49.2

2.95 (2.54; 3.43)

Hypertension1 (%)

10.0

1.44 (1.17; 1.78)

Diabetes Mellitus1 (%)

5.8

2.38 (1.49; 3.83)

LDL-C (mmol/L): mean (SD)

6.58 (1.86)

0.95 (0.91; 0.99)

HDL-C (mmol/L): mean (SD)

1.23 (0.35)

0.32 (0.26; 0.41)

Triglycerides (mmol/L): mean (SD)

1.70 (1.02)

1.14 (1.07; 1.22)

Homocysteine (μmol/L): mean (SD)

12.4 (8.9)

1.08 (1.04; 1.11)2

Lp(a) (mg/L): mean (SD)

338 (419)

1.04 (1.02; 1.06)3

  1. 1 Hypertension and Diabetes Mellitus were analyzed as time-dependent covariates. 2 Hazard-ratio per 5 μmol/L increase Homocysteine. 3 Hazard-ratio per 100 mg/L increase Lp(a). HDL-c = high density lipoprotein cholesterol; LDL-C = low density lipoprotein cholesterol; Lp(a) = apolipoprotein(a); HR = hazard ratio.