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Table 4 Onset of severe knee pain at three years in people aged 50 and over with non-severe knee pain at baseline by body mass index (BMI) category.

From: Disabling knee pain – another consequence of obesity: Results from a prospective cohort study

BMI category at baseline   Severe knee pain at 3 years Unadjusted analysis Adjusted analysisa
  n n (%) RR (95% CI) RRb (95% CI) Potential cases avoidedc (% of all incident cases) RR (95% CI) RRb (95% CI) Potential cases avoidedc (% of all incident cases)
Normald 356 56 (15.7) 1.00 - - 1.00 - -
Overweight 383 67 (17.5) 1.11 (0.80, 1.54) 1.00 7 (4.2) 1.07 (0.74, 1.56) 1.00 4 (2.4)
Obese 148 44 (29.7) 1.89 (1.34, 2.67) 1.70 (1.22, 2.36) 18 (10.8) 1.77 (1.16, 2.69) 1.66 (1.10, 2.52) 18 (10.8)
Total 887 167 (18.8)    25 (15.0)    22 (13.2)
  1. a adjusted for age, gender, deprivation, anxiety, depression, previous knee injury, widespread pain, chronicity of knee pain (3 months or more) at baseline and laterality of knee pain (1 knee or both) at baseline
  2. b obesity category compared to overweight
  3. c number of cases which could have been avoided by reducing overweight people to normal and obese people to overweight
  4. d Normal weight category includes individuals who were underweight.