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Table 1 Reasons for changing medications

From: Management of high-risk patients with hypertension and left ventricular hypertrophy in Germany: differences between cardiac specialists in the inpatient and outpatient setting

Reason

Inpatients (N = 6358) %

Outpatients (N = 2246) %

p value

Lack of efficacy

58.6

67.7

<0.0001

Not tolerated*

7.3

21.1

<0.0001

   Cough (with ACE inhibitors)

35.3

62.1

<0.0001

   Angioedema

25.8

20.6

n.s.

   Others

35.7

20.4

<0.0001

   Not reported

7.5

8.2

n.s.

Contraindication

1.7

1.3

n.s

Drug-drug interaction

1.0

0.6

n.s

Compliance

2.7

4.2

n.s

Patient's request

2.9

5.3

<0.0001

Other reasons

14

6.7

<0.0001

No change

25.4

20.8

<0.0001

  1. n.s., not significant
  2. * Several reasons may apply in an individual patient.