Reason | Inpatients (N = 6358) % | Outpatients (N = 2246) % | p value |
---|---|---|---|
Lack of efficacy | 58.6 | 67.7 | <0.0001 |
Not tolerated* | 7.3 | 21.1 | <0.0001 |
   Cough (with ACE inhibitors) | 35.3 | 62.1 | <0.0001 |
   Angioedema | 25.8 | 20.6 | n.s. |
   Others | 35.7 | 20.4 | <0.0001 |
   Not reported | 7.5 | 8.2 | n.s. |
Contraindication | 1.7 | 1.3 | n.s |
Drug-drug interaction | 1.0 | 0.6 | n.s |
Compliance | 2.7 | 4.2 | n.s |
Patient's request | 2.9 | 5.3 | <0.0001 |
Other reasons | 14 | 6.7 | <0.0001 |
No change | 25.4 | 20.8 | <0.0001 |